Plasma CXCL8 and MCP-1 as surrogate plasma biomarkers of latent tuberculosis infection among household contacts-A cross-sectional study.

Plasma CXCL8 and MCP-1 as surrogate plasma biomarkers of latent tuberculosis infection among household contacts-A cross-sectional study.

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Early detection of latent tuberculosis infection (LTBI) is critical to TB elimination in the current WHO vision of End Tuberculosis Strategy. The study investigates whether detecting plasma cytokines could aid in diagnosing LTBI across household contacts (HHCs) positive for IGRA, HHCs negative for I...

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Main Authors: Sivaprakasam T Selvavinayagam, Bijulal Aswathy, Yean K Yong, Asha Frederick, Lakshmi Murali, Vasudevan Kalaivani, Sree J Karishma, Manivannan Rajeshkumar, Adukkadukkam Anusree, Meganathan Kannan, Natarajan Gopalan, Ramachandran Vignesh, Amudhan Murugesan, Hong Yien Tan, Ying Zhang, Samudi Chandramathi, Munusamy Ponnan Sivasankaran, Pachamuthu Balakrishnan, Sakthivel Govindaraj, Siddappa N Byrareddy, Vijayakumar Velu, Marie Larsson, Esaki M Shankar, Sivadoss Raju
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLOS Global Public Health
Online Access:https://journals.plos.org/globalpublichealth/article/file?id=10.1371/journal.pgph.0002327&type=printable

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