Answering the Big Clinical Questions in Brain Metastasis Management

Management of brain metastases is challenging, both because of the historically guarded prognosis and evolving, more efficacious treatment paradigms for metastatic cancer. This perspective addresses several of the important difficult questions that practitioners treating patients with brain tumors f...

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Main Author: John P. Kirkpatrick
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.834122/full
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author John P. Kirkpatrick
John P. Kirkpatrick
author_facet John P. Kirkpatrick
John P. Kirkpatrick
author_sort John P. Kirkpatrick
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description Management of brain metastases is challenging, both because of the historically guarded prognosis and evolving, more efficacious treatment paradigms for metastatic cancer. This perspective addresses several of the important difficult questions that practitioners treating patients with brain tumors face in the clinic. Successfully answering these questions requires knowledge of the clinical evidence, thoughtful discussion of the patient’s goals of care and collaboration in a multi-disciplinary setting.
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spelling doaj.art-a515a54ff5f246688204307902daacb92022-12-21T17:22:48ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2022-01-011110.3389/fonc.2021.834122834122Answering the Big Clinical Questions in Brain Metastasis ManagementJohn P. Kirkpatrick0John P. Kirkpatrick1Department of Radiation Oncology, Duke Cancer Institute, Durham, NC, United StatesDepartment of Neurosurgery, Duke Cancer Institute, Durham, NC, United StatesManagement of brain metastases is challenging, both because of the historically guarded prognosis and evolving, more efficacious treatment paradigms for metastatic cancer. This perspective addresses several of the important difficult questions that practitioners treating patients with brain tumors face in the clinic. Successfully answering these questions requires knowledge of the clinical evidence, thoughtful discussion of the patient’s goals of care and collaboration in a multi-disciplinary setting.https://www.frontiersin.org/articles/10.3389/fonc.2021.834122/fullbrain metastasesstereotactic radiosurgerywhole-brain radiotherapyhippocampal avoidancepalliative careleptomeningeal disease
spellingShingle John P. Kirkpatrick
John P. Kirkpatrick
Answering the Big Clinical Questions in Brain Metastasis Management
Frontiers in Oncology
brain metastases
stereotactic radiosurgery
whole-brain radiotherapy
hippocampal avoidance
palliative care
leptomeningeal disease
title Answering the Big Clinical Questions in Brain Metastasis Management
title_full Answering the Big Clinical Questions in Brain Metastasis Management
title_fullStr Answering the Big Clinical Questions in Brain Metastasis Management
title_full_unstemmed Answering the Big Clinical Questions in Brain Metastasis Management
title_short Answering the Big Clinical Questions in Brain Metastasis Management
title_sort answering the big clinical questions in brain metastasis management
topic brain metastases
stereotactic radiosurgery
whole-brain radiotherapy
hippocampal avoidance
palliative care
leptomeningeal disease
url https://www.frontiersin.org/articles/10.3389/fonc.2021.834122/full
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