Introduction and Review of Liquid-Liquid Microextraction Method, Development and Applications in Sample Preparation and Extraction
Dispersive liquid-liquid microextraction (DLLME) is a novel sample-preparation technique that provides high enrichment factors from the low volume of aqueous samples. This method has gained wide acceptance due to several advantages, including being inexpensive, fast, easy to develop, easy to operate...
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| Format: | Article |
| Language: | fas |
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Vesnu Publications
2022-10-01
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| Series: | تحقیقات نظام سلامت |
| Subjects: | |
| Online Access: | http://hsr.mui.ac.ir/article-1-1360-en.html |
| _version_ | 1797975402938892288 |
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| author | Sara Karimi-Zeverdegani Samane Khorshidikia Zohreh Mohebian |
| author_facet | Sara Karimi-Zeverdegani Samane Khorshidikia Zohreh Mohebian |
| author_sort | Sara Karimi-Zeverdegani |
| collection | DOAJ |
| description | Dispersive liquid-liquid microextraction (DLLME) is a novel sample-preparation technique that provides high enrichment factors from the low volume of aqueous samples. This method has gained wide acceptance due to several advantages, including being inexpensive, fast, easy to develop, easy to operate with a high enrichment factor, and consuming low volume of organic solvent, which has made it available to almost all analytical laboratories. This review focuses on the improvements that have been made in the DLLME since its introduction in 2006. In this study, the use of DLLME with simultaneous derivatization of analytes, the combination of DLLME with other sample preparation techniques, and the replacement of toxic chlorinated solvents with low toxicity hydrocarbons, alcohols, and ionic liquids were described. Moreover, this paper seeks to describe the use of DLLME to pre-concentrate metal ions and further modifications of this newly developed technique. It briefly describes the various applications of DLLME for several groups of analytes, including pesticides, drugs, phenols, and other compounds, and finally, some limitations and future trends are anticipated. |
| first_indexed | 2024-04-11T04:35:01Z |
| format | Article |
| id | doaj.art-a51629fbaf8f4b4a8f62820e1d39aa45 |
| institution | Directory Open Access Journal |
| issn | 1735-2363 2322-5564 |
| language | fas |
| last_indexed | 2024-04-11T04:35:01Z |
| publishDate | 2022-10-01 |
| publisher | Vesnu Publications |
| record_format | Article |
| series | تحقیقات نظام سلامت |
| spelling | doaj.art-a51629fbaf8f4b4a8f62820e1d39aa452022-12-28T18:41:59ZfasVesnu Publicationsتحقیقات نظام سلامت1735-23632322-55642022-10-01183170185Introduction and Review of Liquid-Liquid Microextraction Method, Development and Applications in Sample Preparation and ExtractionSara Karimi-Zeverdegani0Samane Khorshidikia1Zohreh Mohebian2 Associate Professor, Department of Occupational Health Engineering, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran PhD Student, Student Research Committee AND Department of Occupational Health Engineering, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran PhD Student, Student Research Committee AND Department of Occupational Health Engineering, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran Dispersive liquid-liquid microextraction (DLLME) is a novel sample-preparation technique that provides high enrichment factors from the low volume of aqueous samples. This method has gained wide acceptance due to several advantages, including being inexpensive, fast, easy to develop, easy to operate with a high enrichment factor, and consuming low volume of organic solvent, which has made it available to almost all analytical laboratories. This review focuses on the improvements that have been made in the DLLME since its introduction in 2006. In this study, the use of DLLME with simultaneous derivatization of analytes, the combination of DLLME with other sample preparation techniques, and the replacement of toxic chlorinated solvents with low toxicity hydrocarbons, alcohols, and ionic liquids were described. Moreover, this paper seeks to describe the use of DLLME to pre-concentrate metal ions and further modifications of this newly developed technique. It briefly describes the various applications of DLLME for several groups of analytes, including pesticides, drugs, phenols, and other compounds, and finally, some limitations and future trends are anticipated.http://hsr.mui.ac.ir/article-1-1360-en.htmlliquid-liquid extractionsample preparationwater |
| spellingShingle | Sara Karimi-Zeverdegani Samane Khorshidikia Zohreh Mohebian Introduction and Review of Liquid-Liquid Microextraction Method, Development and Applications in Sample Preparation and Extraction تحقیقات نظام سلامت liquid-liquid extraction sample preparation water |
| title | Introduction and Review of Liquid-Liquid Microextraction Method, Development and Applications in Sample Preparation and Extraction |
| title_full | Introduction and Review of Liquid-Liquid Microextraction Method, Development and Applications in Sample Preparation and Extraction |
| title_fullStr | Introduction and Review of Liquid-Liquid Microextraction Method, Development and Applications in Sample Preparation and Extraction |
| title_full_unstemmed | Introduction and Review of Liquid-Liquid Microextraction Method, Development and Applications in Sample Preparation and Extraction |
| title_short | Introduction and Review of Liquid-Liquid Microextraction Method, Development and Applications in Sample Preparation and Extraction |
| title_sort | introduction and review of liquid liquid microextraction method development and applications in sample preparation and extraction |
| topic | liquid-liquid extraction sample preparation water |
| url | http://hsr.mui.ac.ir/article-1-1360-en.html |
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