Cohort study of microelement status in “healthy” population of Russian megapolis

The aim of the study was at the cohort assessment of microelement status in large city residents classified as “apparently healthy people”. The population study included 2,025 randomly selected middle-aged (2045 years) persons without chronic diseases or acute infectious pathologies. The set of subj...

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Main Authors: Martusevich Andrew K., Karuzin Konstantin A.
Format: Article
Language:English
Published: China Medical University 2019-09-01
Series:BioMedicine
Subjects:
Online Access:https://biomedicine.edp-open.org/articles/bmdcn/full_html/2019/03/bmdcn2019090315/bmdcn2019090315.html
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author Martusevich Andrew K.
Karuzin Konstantin A.
author_facet Martusevich Andrew K.
Karuzin Konstantin A.
author_sort Martusevich Andrew K.
collection DOAJ
description The aim of the study was at the cohort assessment of microelement status in large city residents classified as “apparently healthy people”. The population study included 2,025 randomly selected middle-aged (2045 years) persons without chronic diseases or acute infectious pathologies. The set of subjects was standardized by age and gender. A blood sample was taken once from each person to determine concentrations of microelements. The level of peripheral blood microelements were determined by atomic absorption spectrometry using «Shimadzu AA7000» device (Japan). The study of a large population of city residents demonstrated inhomogeneity in their microelement status. Deficit conditions were found for a number of values, including concentrations of potassium, sodium, nickel, stibium, chromium and cadmium. At the same time, there are large proportions of persons with low plasma concentrations of copper and even lower plasma concentrations of zinc and magnesium. On the contrary, 42% of the persons show high concentrations of lithium. Such disturbances of microelement homeostasis (pre-pathological condition) make it necessary to perform targeted correction for the purpose of preventing the development of pathological conditions associated with microelement deficiencies.
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spelling doaj.art-a5173f59653f4888985dd5aa1edbf7ea2022-12-22T00:22:32ZengChina Medical UniversityBioMedicine2211-80392019-09-01931510.1051/bmdcn/2019090315bmdcn2019090315Cohort study of microelement status in “healthy” population of Russian megapolisMartusevich Andrew K.Karuzin Konstantin A.The aim of the study was at the cohort assessment of microelement status in large city residents classified as “apparently healthy people”. The population study included 2,025 randomly selected middle-aged (2045 years) persons without chronic diseases or acute infectious pathologies. The set of subjects was standardized by age and gender. A blood sample was taken once from each person to determine concentrations of microelements. The level of peripheral blood microelements were determined by atomic absorption spectrometry using «Shimadzu AA7000» device (Japan). The study of a large population of city residents demonstrated inhomogeneity in their microelement status. Deficit conditions were found for a number of values, including concentrations of potassium, sodium, nickel, stibium, chromium and cadmium. At the same time, there are large proportions of persons with low plasma concentrations of copper and even lower plasma concentrations of zinc and magnesium. On the contrary, 42% of the persons show high concentrations of lithium. Such disturbances of microelement homeostasis (pre-pathological condition) make it necessary to perform targeted correction for the purpose of preventing the development of pathological conditions associated with microelement deficiencies.https://biomedicine.edp-open.org/articles/bmdcn/full_html/2019/03/bmdcn2019090315/bmdcn2019090315.htmlTrace elementsBloodPopulationMegapolis
spellingShingle Martusevich Andrew K.
Karuzin Konstantin A.
Cohort study of microelement status in “healthy” population of Russian megapolis
BioMedicine
Trace elements
Blood
Population
Megapolis
title Cohort study of microelement status in “healthy” population of Russian megapolis
title_full Cohort study of microelement status in “healthy” population of Russian megapolis
title_fullStr Cohort study of microelement status in “healthy” population of Russian megapolis
title_full_unstemmed Cohort study of microelement status in “healthy” population of Russian megapolis
title_short Cohort study of microelement status in “healthy” population of Russian megapolis
title_sort cohort study of microelement status in healthy population of russian megapolis
topic Trace elements
Blood
Population
Megapolis
url https://biomedicine.edp-open.org/articles/bmdcn/full_html/2019/03/bmdcn2019090315/bmdcn2019090315.html
work_keys_str_mv AT martusevichandrewk cohortstudyofmicroelementstatusinhealthypopulationofrussianmegapolis
AT karuzinkonstantina cohortstudyofmicroelementstatusinhealthypopulationofrussianmegapolis