Study of Probiotic Effects of <i>Bifidobacterium animalis</i> subsp. <i>lactis</i> BB-12 and <i>Lactobacillus plantarum</i> 299v Strains on Biochemical and Morphometric Parameters of Rabbits after Obesity Induction
This study aimed first to develop an experimental model of obesity and metabolic syndrome over 14 weeks using a diet called “cafeteria”, which is a high-fat diet, to evaluate its consequences on the biochemical and morphometric parameters in ITELV2006 strain rabbits. Second, the trial aimed to evalu...
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MDPI AG
2021-02-01
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| Online Access: | https://www.mdpi.com/2079-7737/10/2/131 |
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| author | Assia Bouaziz Amira Leila Dib Nedjoua Lakhdara Louiza Kadja Elena Espigares Elena Moreno Omar Bouaziz Mohammed Gagaoua |
| author_facet | Assia Bouaziz Amira Leila Dib Nedjoua Lakhdara Louiza Kadja Elena Espigares Elena Moreno Omar Bouaziz Mohammed Gagaoua |
| author_sort | Assia Bouaziz |
| collection | DOAJ |
| description | This study aimed first to develop an experimental model of obesity and metabolic syndrome over 14 weeks using a diet called “cafeteria”, which is a high-fat diet, to evaluate its consequences on the biochemical and morphometric parameters in ITELV2006 strain rabbits. Second, the trial aimed to evaluate the effect of two strains of probiotics, these being <i>Bifidobacterium animalis</i> subsp. <i>lactis</i> BB-12<sup>®</sup> and <i>Lactobacillus plantarum</i> 299v<sup>®</sup>, on the obesity and MetS induced during the first experiment. Overall, the results of the “cafeteria” diet demonstrated significant changes in numerous biochemical and morphometric parameters, reproducing obesity and the main clinical manifestations of the metabolic syndrome in humans. The administration of the two probiotic strains demonstrated an impact on certain parameters of obesity and induced MetS. This study makes it possible to conclude that probiotics could be useful in the treatment of obesity and metabolic syndrome of rabbits, but in a dependent manner. Furthermore, this study evidenced the importance of selecting specific probiotic strains and dosages to achieve desirable results on rabbits or other species. |
| first_indexed | 2024-03-09T05:13:14Z |
| format | Article |
| id | doaj.art-a51b32207c704e0f8b8b6b7ed982e57a |
| institution | Directory Open Access Journal |
| issn | 2079-7737 |
| language | English |
| last_indexed | 2024-03-09T05:13:14Z |
| publishDate | 2021-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biology |
| spelling | doaj.art-a51b32207c704e0f8b8b6b7ed982e57a2023-12-03T12:48:00ZengMDPI AGBiology2079-77372021-02-0110213110.3390/biology10020131Study of Probiotic Effects of <i>Bifidobacterium animalis</i> subsp. <i>lactis</i> BB-12 and <i>Lactobacillus plantarum</i> 299v Strains on Biochemical and Morphometric Parameters of Rabbits after Obesity InductionAssia Bouaziz0Amira Leila Dib1Nedjoua Lakhdara2Louiza Kadja3Elena Espigares4Elena Moreno5Omar Bouaziz6Mohammed Gagaoua7GSPA Research Laboratory, Institut des Sciences Vétérinaires, Université Frères Mentouri Constantine 1, 05 Route de Batna, El-Khroub, Constantine 25000, AlgeriaGSPA Research Laboratory, Institut des Sciences Vétérinaires, Université Frères Mentouri Constantine 1, 05 Route de Batna, El-Khroub, Constantine 25000, AlgeriaGSPA Research Laboratory, Institut des Sciences Vétérinaires, Université Frères Mentouri Constantine 1, 05 Route de Batna, El-Khroub, Constantine 25000, AlgeriaGSPA Research Laboratory, Institut des Sciences Vétérinaires, Université Frères Mentouri Constantine 1, 05 Route de Batna, El-Khroub, Constantine 25000, AlgeriaDepartment of Preventive Medicine and Public Health, Faculty of pharmacy, University of Granada, Campus Universitario de Cartuja, 18071 Granada, SpainDepartment of Preventive Medicine and Public Health, Faculty of pharmacy, University of Granada, Campus Universitario de Cartuja, 18071 Granada, SpainGSPA Research Laboratory, Institut des Sciences Vétérinaires, Université Frères Mentouri Constantine 1, 05 Route de Batna, El-Khroub, Constantine 25000, AlgeriaFood Quality and Sensory Science Department, Teagasc Food Research Centre, Ashtown, D15 DY05 Dublin 15, IrelandThis study aimed first to develop an experimental model of obesity and metabolic syndrome over 14 weeks using a diet called “cafeteria”, which is a high-fat diet, to evaluate its consequences on the biochemical and morphometric parameters in ITELV2006 strain rabbits. Second, the trial aimed to evaluate the effect of two strains of probiotics, these being <i>Bifidobacterium animalis</i> subsp. <i>lactis</i> BB-12<sup>®</sup> and <i>Lactobacillus plantarum</i> 299v<sup>®</sup>, on the obesity and MetS induced during the first experiment. Overall, the results of the “cafeteria” diet demonstrated significant changes in numerous biochemical and morphometric parameters, reproducing obesity and the main clinical manifestations of the metabolic syndrome in humans. The administration of the two probiotic strains demonstrated an impact on certain parameters of obesity and induced MetS. This study makes it possible to conclude that probiotics could be useful in the treatment of obesity and metabolic syndrome of rabbits, but in a dependent manner. Furthermore, this study evidenced the importance of selecting specific probiotic strains and dosages to achieve desirable results on rabbits or other species.https://www.mdpi.com/2079-7737/10/2/131rabbitsfatty dietprobioticsmicrobiotahealthbody weight |
| spellingShingle | Assia Bouaziz Amira Leila Dib Nedjoua Lakhdara Louiza Kadja Elena Espigares Elena Moreno Omar Bouaziz Mohammed Gagaoua Study of Probiotic Effects of <i>Bifidobacterium animalis</i> subsp. <i>lactis</i> BB-12 and <i>Lactobacillus plantarum</i> 299v Strains on Biochemical and Morphometric Parameters of Rabbits after Obesity Induction Biology rabbits fatty diet probiotics microbiota health body weight |
| title | Study of Probiotic Effects of <i>Bifidobacterium animalis</i> subsp. <i>lactis</i> BB-12 and <i>Lactobacillus plantarum</i> 299v Strains on Biochemical and Morphometric Parameters of Rabbits after Obesity Induction |
| title_full | Study of Probiotic Effects of <i>Bifidobacterium animalis</i> subsp. <i>lactis</i> BB-12 and <i>Lactobacillus plantarum</i> 299v Strains on Biochemical and Morphometric Parameters of Rabbits after Obesity Induction |
| title_fullStr | Study of Probiotic Effects of <i>Bifidobacterium animalis</i> subsp. <i>lactis</i> BB-12 and <i>Lactobacillus plantarum</i> 299v Strains on Biochemical and Morphometric Parameters of Rabbits after Obesity Induction |
| title_full_unstemmed | Study of Probiotic Effects of <i>Bifidobacterium animalis</i> subsp. <i>lactis</i> BB-12 and <i>Lactobacillus plantarum</i> 299v Strains on Biochemical and Morphometric Parameters of Rabbits after Obesity Induction |
| title_short | Study of Probiotic Effects of <i>Bifidobacterium animalis</i> subsp. <i>lactis</i> BB-12 and <i>Lactobacillus plantarum</i> 299v Strains on Biochemical and Morphometric Parameters of Rabbits after Obesity Induction |
| title_sort | study of probiotic effects of i bifidobacterium animalis i subsp i lactis i bb 12 and i lactobacillus plantarum i 299v strains on biochemical and morphometric parameters of rabbits after obesity induction |
| topic | rabbits fatty diet probiotics microbiota health body weight |
| url | https://www.mdpi.com/2079-7737/10/2/131 |
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