Reinforcement learning for patient-specific optimal stenting of intracranial aneurysms

Abstract Developing new capabilities to predict the risk of intracranial aneurysm rupture and to improve treatment outcomes in the follow-up of endovascular repair is of tremendous medical and societal interest, both to support decision-making and assessment of treatment options by medical doctors,...

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Bibliographic Details
Main Authors: E. Hachem, P. Meliga, A. Goetz, P. Jeken Rico, J. Viquerat, A. Larcher, R. Valette, A. F. Sanches, V. Lannelongue, H. Ghraieb, R. Nemer, Y. Ozpeynirci, T. Liebig
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-34007-z
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Summary:Abstract Developing new capabilities to predict the risk of intracranial aneurysm rupture and to improve treatment outcomes in the follow-up of endovascular repair is of tremendous medical and societal interest, both to support decision-making and assessment of treatment options by medical doctors, and to improve the life quality and expectancy of patients. This study aims at identifying and characterizing novel flow-deviator stent devices through a high-fidelity computational framework that combines state-of-the-art numerical methods to accurately describe the mechanical exchanges between the blood flow, the aneurysm, and the flow-deviator and deep reinforcement learning algorithms to identify a new stent concepts enabling patient-specific treatment via accurate adjustment of the functional parameters in the implanted state.
ISSN:2045-2322