Synthesis of the Benzo-fused Indolizidine Alkaloid Mimics
A general synthesis of various benzo-fused indolizidine alkaloid mimics has been developed. The indolizidine derivatives 8 were prepared via heteroaryl Grignard addition to N-acylpyridinium salts followed by an intramolecular Heck cyclization. Further substitution reactions were developed to demonst...
Main Authors: | Daniel L. Comins, Kazuhiro Higuchi |
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Format: | Article |
Language: | English |
Published: |
Beilstein-Institut
2007-11-01
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Series: | Beilstein Journal of Organic Chemistry |
Online Access: | https://doi.org/10.1186/1860-5397-3-42 |
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