Synthesis of the Benzo-fused Indolizidine Alkaloid Mimics

A general synthesis of various benzo-fused indolizidine alkaloid mimics has been developed. The indolizidine derivatives 8 were prepared via heteroaryl Grignard addition to N-acylpyridinium salts followed by an intramolecular Heck cyclization. Further substitution reactions were developed to demonst...

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Bibliographic Details
Main Authors: Daniel L. Comins, Kazuhiro Higuchi
Format: Article
Language:English
Published: Beilstein-Institut 2007-11-01
Series:Beilstein Journal of Organic Chemistry
Online Access:https://doi.org/10.1186/1860-5397-3-42

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