RELIEF OF POST-TONSILLECTOMY PAIN BY TOPICAL APPLICATION OF BUPIVACAINE

Objective: To determine the relief of pain after tonsillectomy by application of topical 0.5% bupivacaine. Methodology: This prospective single-blind study was conducted at Departments of ENT, Mufti Mehmood MemorialTeaching Hospital and District Headquarter Teaching Hospital, Dera Ismail Khan from...

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Main Authors: Muhammad Ismail Khan, syed fahim shah, Muhammad, Kamran Iqbal
Format: Article
Language:English
Published: Khyber Medical University 2012-12-01
Series:Khyber Medical University Journal
Online Access:https://www.kmuj.kmu.edu.pk/article/view/10879
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author Muhammad Ismail Khan
syed fahim shah
Muhammad ,
Kamran Iqbal
author_facet Muhammad Ismail Khan
syed fahim shah
Muhammad ,
Kamran Iqbal
author_sort Muhammad Ismail Khan
collection DOAJ
description Objective: To determine the relief of pain after tonsillectomy by application of topical 0.5% bupivacaine. Methodology: This prospective single-blind study was conducted at Departments of ENT, Mufti Mehmood MemorialTeaching Hospital and District Headquarter Teaching Hospital, Dera Ismail Khan from January 2011 to June 2012. Subjectsof either sex, aging 10-35 years with history of recurrent episodes of acute tonsillitis were included. Those withadenotonsillectomy, with history of acute tonsillitis within three weeks, bleeding diathesis, suspicious of malignancy,or hypersensitivity to bupivacaine were excluded. Subjects were divided into group 1 (treatment group) and 2 (controlgroup) of 48 patients each on convenient sampling method. Patients in group 1 received a topical application of bupivacainegauze soaked in 5 ml of 0.5% bupivacaine solution for five minutes in both tonsillar fossae while patients ingroup 2, received nothing. The post operative pain score was assessed on Visual Analogue Scale (VAS) and comparedbetween the groups at 1, 3 and 8 hours. Results: Out of 96 subjects (48 in each group), 56 (58.3%) were male and 40 (41.7%) female. Mean Pain Score was5.27±2.811 in group 1 & 6.02±2.914 group 2 at 1 hour (p=0.203); 4.81±2.750 in group 1 & 5.60±2.944 group 2 at 3hour (p=0.177) and 4.35±2.605 in group 1 & 5.08±2.901 group 2 at 8 hour (p=0.198). Conclusion: Topical application of 0.5% bupivacaine provides no significant pain relief in post-tonsillectomy patientsin first 8 hours. Key Words: Bupivacaine topical, Post-tonsillectomy pain, Visual Analogue Scale.   This article may be cited as: Khan MI, Shah SF, Muhammad, Iqbal K. Relief of post-tonsillectomy pain by topicalapplication of bupivacaine. Khyber Med Univ J 2012; 4(4): 183-186.
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spelling doaj.art-a51d719145134fb6b369d44e73dcd5032022-12-21T23:34:02ZengKhyber Medical UniversityKhyber Medical University Journal2305-26432305-26512012-12-014418318610879RELIEF OF POST-TONSILLECTOMY PAIN BY TOPICAL APPLICATION OF BUPIVACAINEMuhammad Ismail Khan0syed fahim shah1Muhammad ,2Kamran Iqbal3Departments of ENT, Mufti Mehmood Memorial Teaching Hospital and DHQ Teaching Hospital, Gomal Medical College, D.I.Khan, KPK, PakistanKIMSSenior Registrar, Department of Ophthalmology, Mufti Mehmood Memorial Teaching Hospital/ Gomal Medical College, D.I.Khan ,KPK, PakistanAssistant Professor, Department of ENT, District Headquarter Teaching Hospital/ Gomal Medical College, D.I.Khan, KPK, PakistanObjective: To determine the relief of pain after tonsillectomy by application of topical 0.5% bupivacaine. Methodology: This prospective single-blind study was conducted at Departments of ENT, Mufti Mehmood MemorialTeaching Hospital and District Headquarter Teaching Hospital, Dera Ismail Khan from January 2011 to June 2012. Subjectsof either sex, aging 10-35 years with history of recurrent episodes of acute tonsillitis were included. Those withadenotonsillectomy, with history of acute tonsillitis within three weeks, bleeding diathesis, suspicious of malignancy,or hypersensitivity to bupivacaine were excluded. Subjects were divided into group 1 (treatment group) and 2 (controlgroup) of 48 patients each on convenient sampling method. Patients in group 1 received a topical application of bupivacainegauze soaked in 5 ml of 0.5% bupivacaine solution for five minutes in both tonsillar fossae while patients ingroup 2, received nothing. The post operative pain score was assessed on Visual Analogue Scale (VAS) and comparedbetween the groups at 1, 3 and 8 hours. Results: Out of 96 subjects (48 in each group), 56 (58.3%) were male and 40 (41.7%) female. Mean Pain Score was5.27±2.811 in group 1 & 6.02±2.914 group 2 at 1 hour (p=0.203); 4.81±2.750 in group 1 & 5.60±2.944 group 2 at 3hour (p=0.177) and 4.35±2.605 in group 1 & 5.08±2.901 group 2 at 8 hour (p=0.198). Conclusion: Topical application of 0.5% bupivacaine provides no significant pain relief in post-tonsillectomy patientsin first 8 hours. Key Words: Bupivacaine topical, Post-tonsillectomy pain, Visual Analogue Scale.   This article may be cited as: Khan MI, Shah SF, Muhammad, Iqbal K. Relief of post-tonsillectomy pain by topicalapplication of bupivacaine. Khyber Med Univ J 2012; 4(4): 183-186.https://www.kmuj.kmu.edu.pk/article/view/10879
spellingShingle Muhammad Ismail Khan
syed fahim shah
Muhammad ,
Kamran Iqbal
RELIEF OF POST-TONSILLECTOMY PAIN BY TOPICAL APPLICATION OF BUPIVACAINE
Khyber Medical University Journal
title RELIEF OF POST-TONSILLECTOMY PAIN BY TOPICAL APPLICATION OF BUPIVACAINE
title_full RELIEF OF POST-TONSILLECTOMY PAIN BY TOPICAL APPLICATION OF BUPIVACAINE
title_fullStr RELIEF OF POST-TONSILLECTOMY PAIN BY TOPICAL APPLICATION OF BUPIVACAINE
title_full_unstemmed RELIEF OF POST-TONSILLECTOMY PAIN BY TOPICAL APPLICATION OF BUPIVACAINE
title_short RELIEF OF POST-TONSILLECTOMY PAIN BY TOPICAL APPLICATION OF BUPIVACAINE
title_sort relief of post tonsillectomy pain by topical application of bupivacaine
url https://www.kmuj.kmu.edu.pk/article/view/10879
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