Modeling of an immobilized lipase tubular reactor for the production of glycerol and fatty acids from oils

Advances in the design of a bioreactor in the fats and oils industry have permitted the hydrolysis of triglycerides in mild conditions and improved productivity while avoiding the formation of unwanted byproducts. The present work develops a mathematical model that describes the hydrolytic activity...

Full description

Bibliographic Details
Main Authors: Sebastián Oddone, Mariano Grasselli, Anahí Cuellas
Format: Article
Language:English
Published: Consejo Superior de Investigaciones Científicas 2010-06-01
Series:Grasas y Aceites
Subjects:
Online Access:http://grasasyaceites.revistas.csic.es/index.php/grasasyaceites/article/view/827
_version_ 1818457334279569408
author Sebastián Oddone
Mariano Grasselli
Anahí Cuellas
author_facet Sebastián Oddone
Mariano Grasselli
Anahí Cuellas
author_sort Sebastián Oddone
collection DOAJ
description Advances in the design of a bioreactor in the fats and oils industry have permitted the hydrolysis of triglycerides in mild conditions and improved productivity while avoiding the formation of unwanted byproducts. The present work develops a mathematical model that describes the hydrolytic activity of a tubular reactor with immobilized lipases for the production of glycerol and fatty acids from the oil trade. Runge Kutta’s numerical method of high order has been applied, considering that there is no accumulation of the substratum in the surface of the membrane, where the enzyme is. At the same time, different equations based on the kinetic model of Michaelis Mentens and the Ping-Pong bi-bi mechanism were examined. Experimental data in discontinuous systems are the basis for the development of the quantitative mathematical model that was used to simulate the process computationally. The obtained results allow for optimizing both the operative variables and the economic aspects of industrial processes.
first_indexed 2024-12-14T22:40:55Z
format Article
id doaj.art-a51ed49eb9214713bc398e6f465ac6f6
institution Directory Open Access Journal
issn 0017-3495
1988-4214
language English
last_indexed 2024-12-14T22:40:55Z
publishDate 2010-06-01
publisher Consejo Superior de Investigaciones Científicas
record_format Article
series Grasas y Aceites
spelling doaj.art-a51ed49eb9214713bc398e6f465ac6f62022-12-21T22:44:58ZengConsejo Superior de Investigaciones CientíficasGrasas y Aceites0017-34951988-42142010-06-0161217518210.3989/gya.087609813Modeling of an immobilized lipase tubular reactor for the production of glycerol and fatty acids from oilsSebastián Oddone0Mariano Grasselli1Anahí Cuellas2Instituto de Tecnología, Facultad de Ingeniería y Ciencias Exactas, Universidad Argentina de la EmpresaUniversidad Nacional de Quilmes Roque Sáenz PeñaUniversidad Nacional de Quilmes Roque Sáenz PeñaAdvances in the design of a bioreactor in the fats and oils industry have permitted the hydrolysis of triglycerides in mild conditions and improved productivity while avoiding the formation of unwanted byproducts. The present work develops a mathematical model that describes the hydrolytic activity of a tubular reactor with immobilized lipases for the production of glycerol and fatty acids from the oil trade. Runge Kutta’s numerical method of high order has been applied, considering that there is no accumulation of the substratum in the surface of the membrane, where the enzyme is. At the same time, different equations based on the kinetic model of Michaelis Mentens and the Ping-Pong bi-bi mechanism were examined. Experimental data in discontinuous systems are the basis for the development of the quantitative mathematical model that was used to simulate the process computationally. The obtained results allow for optimizing both the operative variables and the economic aspects of industrial processes.http://grasasyaceites.revistas.csic.es/index.php/grasasyaceites/article/view/827bioreactorimmobilizationlipasemodelingoilssimulation
spellingShingle Sebastián Oddone
Mariano Grasselli
Anahí Cuellas
Modeling of an immobilized lipase tubular reactor for the production of glycerol and fatty acids from oils
Grasas y Aceites
bioreactor
immobilization
lipase
modeling
oils
simulation
title Modeling of an immobilized lipase tubular reactor for the production of glycerol and fatty acids from oils
title_full Modeling of an immobilized lipase tubular reactor for the production of glycerol and fatty acids from oils
title_fullStr Modeling of an immobilized lipase tubular reactor for the production of glycerol and fatty acids from oils
title_full_unstemmed Modeling of an immobilized lipase tubular reactor for the production of glycerol and fatty acids from oils
title_short Modeling of an immobilized lipase tubular reactor for the production of glycerol and fatty acids from oils
title_sort modeling of an immobilized lipase tubular reactor for the production of glycerol and fatty acids from oils
topic bioreactor
immobilization
lipase
modeling
oils
simulation
url http://grasasyaceites.revistas.csic.es/index.php/grasasyaceites/article/view/827
work_keys_str_mv AT sebastianoddone modelingofanimmobilizedlipasetubularreactorfortheproductionofglycerolandfattyacidsfromoils
AT marianograsselli modelingofanimmobilizedlipasetubularreactorfortheproductionofglycerolandfattyacidsfromoils
AT anahicuellas modelingofanimmobilizedlipasetubularreactorfortheproductionofglycerolandfattyacidsfromoils