Symptom burden, fatigue, sleep quality and perceived social support in hemodialysis patients with musculoskeletal discomfort: a single center experience from Egypt
Abstract Background and aims Musculoskeletal disorders (MSDs) are commonly encountered in hemodialysis (HD) patients. However, the causes linked to these disorders are still partially defined. The aim of this study was to determine the frequency of MSDs and their relationship to a variety of clinico...
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| Format: | Article |
| Language: | English |
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BMC
2023-10-01
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| Series: | BMC Musculoskeletal Disorders |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12891-023-06910-z |
| _version_ | 1797578691546447872 |
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| author | Mohammed Kamal Nassar Samar Tharwat Sara M. Abdel-Gawad Rabab Elrefaey Alaa A. Elsawi Abdelrahman Mohamed Elsayed Eman Nagy Shimaa Shabaka Rasha Samir Shemies |
| author_facet | Mohammed Kamal Nassar Samar Tharwat Sara M. Abdel-Gawad Rabab Elrefaey Alaa A. Elsawi Abdelrahman Mohamed Elsayed Eman Nagy Shimaa Shabaka Rasha Samir Shemies |
| author_sort | Mohammed Kamal Nassar |
| collection | DOAJ |
| description | Abstract Background and aims Musculoskeletal disorders (MSDs) are commonly encountered in hemodialysis (HD) patients. However, the causes linked to these disorders are still partially defined. The aim of this study was to determine the frequency of MSDs and their relationship to a variety of clinico-social characteristics such as sleep quality, mood disorders, fatigue, and social support, in addition to the patients’ clinical and therapeutic profile. Method The study included 94 patients on maintenance HD. Clinical and Sociodemographic data was gathered. To investigate the prevalence and trends of MSDs, the Nordic Musculoskeletal Questionnaire (NMQ-E) was employed. Patients completed the modified Edmonton Symptom Assessment System, Pittsburgh Sleep Quality Index (PSQI), multidimensional Fatigue Inventory (MFI-20), and Perceived Social Support from Family Scales. Univariate and multivariate regression analysis were used to assess the determinants of MSDs. Results The patients' mean age was 49.73 and 59.6% were males. Seventy-two percent of patients were afflicted by MSDs. Knee pain (48.9%), low back pain (43.6%), shoulder pain (41.6%), hip/thigh pain (35.1%), and neck pains (35.1%) were the most reported MSD domains. Pain (p = 0.001), fatigue (p = 0.01), depression (p = 0.015), and anxiety (p = 0.003) scores were substantially higher in patients with MSDs. Furthermore, patients with MSDs engaged in less physical activity (p = 0.02) and perceived less social support (p = 0.029). Patients with MSDs had lower subjective sleep quality, daytime dysfunction domains, and global PSQI scores (p = 0.02, 0.031, 0.036, respectively). Female gender (p = 0.013), fatigue (p = 0.012), depression (p = 0.014), anxiety (p = 0.004), lower activity (p = 0.029), and PSQI score (0.027), use of erythropoiesis-stimulating agents (ESAs), antihypertensive drugs, calcium and Iron supplementation were all significantly associated with MSDs. At the multivariable regression model, administration of ESAs (p = 0.017) and pain score (p = 0.040) were the only independent variables associated with the outcome. Conclusion MSDs are quite common among HD patients. Female gender, pain, fatigue, depression, anxiety, reduced activity, poor sleep quality, and use of ESAs are all significantly associated with MSDs in HD patients. Patients with MSD perceived less social support compared to the other group. Patients treated with antihypertensive drugs, calcium and iron supplements were more likely to suffer MSDs. |
| first_indexed | 2024-03-10T22:25:20Z |
| format | Article |
| id | doaj.art-a521074ee05e43c3bd01c55cc555479a |
| institution | Directory Open Access Journal |
| issn | 1471-2474 |
| language | English |
| last_indexed | 2024-03-10T22:25:20Z |
| publishDate | 2023-10-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Musculoskeletal Disorders |
| spelling | doaj.art-a521074ee05e43c3bd01c55cc555479a2023-11-19T12:08:20ZengBMCBMC Musculoskeletal Disorders1471-24742023-10-0124111210.1186/s12891-023-06910-zSymptom burden, fatigue, sleep quality and perceived social support in hemodialysis patients with musculoskeletal discomfort: a single center experience from EgyptMohammed Kamal Nassar0Samar Tharwat1Sara M. Abdel-Gawad2Rabab Elrefaey3Alaa A. Elsawi4Abdelrahman Mohamed Elsayed5Eman Nagy6Shimaa Shabaka7Rasha Samir Shemies8Mansoura Nephrology & Dialysis Unit (MNDU), Faculty of Medicine, Mansoura UniversityRheumatology & Immunology Unit, Department of Internal Medicine, Faculty of Medicine, Mansoura UniversityMansoura Nephrology & Dialysis Unit (MNDU), Faculty of Medicine, Mansoura UniversityMansoura Nephrology & Dialysis Unit (MNDU), Faculty of Medicine, Mansoura UniversityMansoura Nephrology & Dialysis Unit (MNDU), Faculty of Medicine, Mansoura UniversityFaculty of Medicine, Mansoura UniversityMansoura Nephrology & Dialysis Unit (MNDU), Faculty of Medicine, Mansoura UniversityMansoura Nephrology & Dialysis Unit (MNDU), Faculty of Medicine, Mansoura UniversityMansoura Nephrology & Dialysis Unit (MNDU), Faculty of Medicine, Mansoura UniversityAbstract Background and aims Musculoskeletal disorders (MSDs) are commonly encountered in hemodialysis (HD) patients. However, the causes linked to these disorders are still partially defined. The aim of this study was to determine the frequency of MSDs and their relationship to a variety of clinico-social characteristics such as sleep quality, mood disorders, fatigue, and social support, in addition to the patients’ clinical and therapeutic profile. Method The study included 94 patients on maintenance HD. Clinical and Sociodemographic data was gathered. To investigate the prevalence and trends of MSDs, the Nordic Musculoskeletal Questionnaire (NMQ-E) was employed. Patients completed the modified Edmonton Symptom Assessment System, Pittsburgh Sleep Quality Index (PSQI), multidimensional Fatigue Inventory (MFI-20), and Perceived Social Support from Family Scales. Univariate and multivariate regression analysis were used to assess the determinants of MSDs. Results The patients' mean age was 49.73 and 59.6% were males. Seventy-two percent of patients were afflicted by MSDs. Knee pain (48.9%), low back pain (43.6%), shoulder pain (41.6%), hip/thigh pain (35.1%), and neck pains (35.1%) were the most reported MSD domains. Pain (p = 0.001), fatigue (p = 0.01), depression (p = 0.015), and anxiety (p = 0.003) scores were substantially higher in patients with MSDs. Furthermore, patients with MSDs engaged in less physical activity (p = 0.02) and perceived less social support (p = 0.029). Patients with MSDs had lower subjective sleep quality, daytime dysfunction domains, and global PSQI scores (p = 0.02, 0.031, 0.036, respectively). Female gender (p = 0.013), fatigue (p = 0.012), depression (p = 0.014), anxiety (p = 0.004), lower activity (p = 0.029), and PSQI score (0.027), use of erythropoiesis-stimulating agents (ESAs), antihypertensive drugs, calcium and Iron supplementation were all significantly associated with MSDs. At the multivariable regression model, administration of ESAs (p = 0.017) and pain score (p = 0.040) were the only independent variables associated with the outcome. Conclusion MSDs are quite common among HD patients. Female gender, pain, fatigue, depression, anxiety, reduced activity, poor sleep quality, and use of ESAs are all significantly associated with MSDs in HD patients. Patients with MSD perceived less social support compared to the other group. Patients treated with antihypertensive drugs, calcium and iron supplements were more likely to suffer MSDs.https://doi.org/10.1186/s12891-023-06910-zMusculoskeletal disorders (MSDs)End stage kidney diseaseHemodialysisFatigueSymptom burdenSleep quality |
| spellingShingle | Mohammed Kamal Nassar Samar Tharwat Sara M. Abdel-Gawad Rabab Elrefaey Alaa A. Elsawi Abdelrahman Mohamed Elsayed Eman Nagy Shimaa Shabaka Rasha Samir Shemies Symptom burden, fatigue, sleep quality and perceived social support in hemodialysis patients with musculoskeletal discomfort: a single center experience from Egypt BMC Musculoskeletal Disorders Musculoskeletal disorders (MSDs) End stage kidney disease Hemodialysis Fatigue Symptom burden Sleep quality |
| title | Symptom burden, fatigue, sleep quality and perceived social support in hemodialysis patients with musculoskeletal discomfort: a single center experience from Egypt |
| title_full | Symptom burden, fatigue, sleep quality and perceived social support in hemodialysis patients with musculoskeletal discomfort: a single center experience from Egypt |
| title_fullStr | Symptom burden, fatigue, sleep quality and perceived social support in hemodialysis patients with musculoskeletal discomfort: a single center experience from Egypt |
| title_full_unstemmed | Symptom burden, fatigue, sleep quality and perceived social support in hemodialysis patients with musculoskeletal discomfort: a single center experience from Egypt |
| title_short | Symptom burden, fatigue, sleep quality and perceived social support in hemodialysis patients with musculoskeletal discomfort: a single center experience from Egypt |
| title_sort | symptom burden fatigue sleep quality and perceived social support in hemodialysis patients with musculoskeletal discomfort a single center experience from egypt |
| topic | Musculoskeletal disorders (MSDs) End stage kidney disease Hemodialysis Fatigue Symptom burden Sleep quality |
| url | https://doi.org/10.1186/s12891-023-06910-z |
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