Two Cases of Unilateral Ashy Dermatosis

Ashy dermatosis is a typically asymptomatic disease of unknown origin that causes symmetrical gray spots to appear on the trunk and extremities. We report 2 cases of ashy dermatosis with unilateral distribution. To our knowledge, only 5 cases of ashy dermatosis with unilateral lesion have been repor...

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Main Authors: Hisayoshi Imanishi, Daisuke Tsuruta, Hiromi Kobayashi, Masamitsu Ishii, Koichi Nakagawa
Format: Article
Language:English
Published: Karger Publishers 2011-01-01
Series:Case Reports in Dermatology
Subjects:
Online Access:http://www.karger.com/Article/FullText/323663
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author Hisayoshi Imanishi
Daisuke Tsuruta
Hiromi Kobayashi
Masamitsu Ishii
Koichi Nakagawa
author_facet Hisayoshi Imanishi
Daisuke Tsuruta
Hiromi Kobayashi
Masamitsu Ishii
Koichi Nakagawa
author_sort Hisayoshi Imanishi
collection DOAJ
description Ashy dermatosis is a typically asymptomatic disease of unknown origin that causes symmetrical gray spots to appear on the trunk and extremities. We report 2 cases of ashy dermatosis with unilateral distribution. To our knowledge, only 5 cases of ashy dermatosis with unilateral lesion have been reported so far. Case 1: an 11-year-old woman presented with asymptomatic slate-gray pigmented plaques on the left trunk and left upper arm. The skin biopsy specimen demonstrated a mild lymphohistiocytotic infiltrate in the upper dermis with epidermal and dermal melanosis. Q-Switched ruby laser did not improve such lesions. Case 2: a 21-year-old man was referred to our hospital because of asymptomatic slate-gray pigmented plaques on the left trunk and left upper arm. Histopathological findings were compatible with a mild lymphocytic infiltration with melanin incontinence in the upper dermis. The mechanism that governs unilateral distribution of ashy dermatosis, including in our cases, remains unclear.
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spelling doaj.art-a5242a7d95ef47f6865fa8012e1555cd2022-12-21T17:48:35ZengKarger PublishersCase Reports in Dermatology1662-65672011-01-01311410.1159/000323663323663Two Cases of Unilateral Ashy DermatosisHisayoshi ImanishiDaisuke TsurutaHiromi KobayashiMasamitsu IshiiKoichi NakagawaAshy dermatosis is a typically asymptomatic disease of unknown origin that causes symmetrical gray spots to appear on the trunk and extremities. We report 2 cases of ashy dermatosis with unilateral distribution. To our knowledge, only 5 cases of ashy dermatosis with unilateral lesion have been reported so far. Case 1: an 11-year-old woman presented with asymptomatic slate-gray pigmented plaques on the left trunk and left upper arm. The skin biopsy specimen demonstrated a mild lymphohistiocytotic infiltrate in the upper dermis with epidermal and dermal melanosis. Q-Switched ruby laser did not improve such lesions. Case 2: a 21-year-old man was referred to our hospital because of asymptomatic slate-gray pigmented plaques on the left trunk and left upper arm. Histopathological findings were compatible with a mild lymphocytic infiltration with melanin incontinence in the upper dermis. The mechanism that governs unilateral distribution of ashy dermatosis, including in our cases, remains unclear.http://www.karger.com/Article/FullText/323663Ashy dermatosisUnilateralErythema dyschromicum perstans
spellingShingle Hisayoshi Imanishi
Daisuke Tsuruta
Hiromi Kobayashi
Masamitsu Ishii
Koichi Nakagawa
Two Cases of Unilateral Ashy Dermatosis
Case Reports in Dermatology
Ashy dermatosis
Unilateral
Erythema dyschromicum perstans
title Two Cases of Unilateral Ashy Dermatosis
title_full Two Cases of Unilateral Ashy Dermatosis
title_fullStr Two Cases of Unilateral Ashy Dermatosis
title_full_unstemmed Two Cases of Unilateral Ashy Dermatosis
title_short Two Cases of Unilateral Ashy Dermatosis
title_sort two cases of unilateral ashy dermatosis
topic Ashy dermatosis
Unilateral
Erythema dyschromicum perstans
url http://www.karger.com/Article/FullText/323663
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AT hiromikobayashi twocasesofunilateralashydermatosis
AT masamitsuishii twocasesofunilateralashydermatosis
AT koichinakagawa twocasesofunilateralashydermatosis