Preparation of Curcumin-Eudragit<sup>®</sup> E PO Solid Dispersions with Gradient Temperature through Hot-Melt Extrusion

Preparation of Curcumin-Eudragit<sup>®</sup> E PO Solid Dispersions with Gradient Temperature through Hot-Melt Extrusion

Hot-melt extrusion (HME) has great advantages for the preparation of solid dispersion (SD), for instance, it does not require any organic solvents. Nevertheless, its application to high-melting-point and thermosensitive drugs has been rarely reported. In this study, thermally unstable curcumin (Cur)...

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Bibliographic Details
Main Authors: Wenling Fan, Xiaotong Zhang, Wenjing Zhu, Xinyi Zhang, Liuqing Di
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Molecules
Subjects:
insoluble
dissolution
thermo-sensitive
Online Access:https://www.mdpi.com/1420-3049/26/16/4964

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