F-Box Protein 43, Stabilized by N6-Methyladenosine Methylation, Enhances Hepatocellular Carcinoma Cell Growth and Invasion via Promoting p53 Degradation in a Ubiquitin Conjugating Enzyme E2 C-Dependent Manner

F-Box Protein 43, Stabilized by N6-Methyladenosine Methylation, Enhances Hepatocellular Carcinoma Cell Growth and Invasion via Promoting p53 Degradation in a Ubiquitin Conjugating Enzyme E2 C-Dependent Manner

The roles of F-box protein 43 (FBXO43) in carcinogenesis have been rarely revealed. The present study investigates the expression, function, and underlying mechanism of FBXO43 in hepatocellular carcinoma (HCC). Firstly, the expression and clinical significance of FBXO43 in HCC were investigated bioi...

Full description

Bibliographic Details
Main Authors: Huijun Zhou, Chong Zeng, Jie Liu, Haijun Luo, Wei Huang
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Cancers
Subjects:
HCC
FBXO43
m6A modification
p53
UBE2C
Online Access:https://www.mdpi.com/2072-6694/15/3/957

Internet

https://www.mdpi.com/2072-6694/15/3/957

Similar Items