Twin pregnancies with uterine fibroids are not at increased risk for obstetric complications: single center cohort study
Abstract Background Twin pregnancies with uterine fibroid(s) (UFs) may not be at increased risk for obstetric complications compared to those without UFs. However, there was no reported comparison study with obstetric outcomes and complications of twin pregnancy after myomectomy. We aimed to compare...
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| Format: | Article |
| Language: | English |
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BMC
2020-04-01
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| Series: | BMC Pregnancy and Childbirth |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12884-020-02908-w |
| _version_ | 1818540549197529088 |
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| author | Mi-La Kim Kirim Hong Sohyun Kim Min Jin Lee Sung Shin Shim Yoon-Mi Hur Joong Sik Shin |
| author_facet | Mi-La Kim Kirim Hong Sohyun Kim Min Jin Lee Sung Shin Shim Yoon-Mi Hur Joong Sik Shin |
| author_sort | Mi-La Kim |
| collection | DOAJ |
| description | Abstract Background Twin pregnancies with uterine fibroid(s) (UFs) may not be at increased risk for obstetric complications compared to those without UFs. However, there was no reported comparison study with obstetric outcomes and complications of twin pregnancy after myomectomy. We aimed to compare the pregnancy outcomes in twin pregnancies with or without uterine fibroid(s), and also compared in patients with previous myomectomy history in Korean women. Methods A cohort of twin pregnancies delivered in a single institution between January 2011 and March 2019 were retrospectively analyzed. UFs group was defined by the presence of UFs during pregnancy (≥1 fibroid, measuring ≥2 cm or multiple fibroids regardless of the size). Previous myomectomy group included patients with history of abdominal or laparoscopic or hysteroscopic myomectomy of ≥1 fibroid, measuring ≥2 cm or multiple fibroids whatever the size. Patients with monochorionic monoamniotic twins, myoma less than 2 cm in size, missed abortion or intrauterine fetal death (IUFD) of one fetus before 14 weeks, history of previous conization, and uterine anomalies were excluded. Pregnancy outcomes and obstetric complications were compared. Result A total 1388 patients were included in this study, 191 (13.8%) had UFs and 89 (6.4%) had a history of myomectomy. Maternal age was younger in non-UFs group and primiparity was more common in UFs group (p < 0.001, and p = 0.019). No significant differences were found in the gestational age at delivery (p = 0.657), delivery before 37 weeks (p = 0.662), delivery before 34 weeks (p = 0.340), and sum of birth weight of twin (p = 0.307). There were also no statistical differences in rates of obstetrical complications, such as preeclampsia, gestational diabetes mellitus, placenta previa, placenta abruption, cerclage, small for gestational age, IUFD, postpartum hemorrhage and peripartum transfusion or ICU care. These obstetrical outcomes and complications showed no statistical differences between UFs group and previous myomectomy group. Conclusion In patients with twin pregnancies, the presence of UFs or history of previous myomectomy did not relate to negative effects on pregnancy outcomes and obstetrical complications. |
| first_indexed | 2024-12-11T21:56:50Z |
| format | Article |
| id | doaj.art-a528e1ed5acd473bac8c6c8850e591b4 |
| institution | Directory Open Access Journal |
| issn | 1471-2393 |
| language | English |
| last_indexed | 2024-12-11T21:56:50Z |
| publishDate | 2020-04-01 |
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| series | BMC Pregnancy and Childbirth |
| spelling | doaj.art-a528e1ed5acd473bac8c6c8850e591b42022-12-22T00:49:17ZengBMCBMC Pregnancy and Childbirth1471-23932020-04-0120111010.1186/s12884-020-02908-wTwin pregnancies with uterine fibroids are not at increased risk for obstetric complications: single center cohort studyMi-La Kim0Kirim Hong1Sohyun Kim2Min Jin Lee3Sung Shin Shim4Yoon-Mi Hur5Joong Sik Shin6Department of Obstetrics and Gynecology, CHA Gangnam Medical Center, CHA UniversityDepartment of Obstetrics and Gynecology, CHA Gangnam Medical Center, CHA UniversityDepartment of Obstetrics and Gynecology, CHA Gangnam Medical Center, CHA UniversityDepartment of Obstetrics and Gynecology, CHA Gangnam Medical Center, CHA UniversityDepartment of Obstetrics and Gynecology, CHA Gangnam Medical Center, CHA UniversityCollege of General Education, Kookmin UniversityDepartment of Obstetrics and Gynecology, CHA Gangnam Medical Center, CHA UniversityAbstract Background Twin pregnancies with uterine fibroid(s) (UFs) may not be at increased risk for obstetric complications compared to those without UFs. However, there was no reported comparison study with obstetric outcomes and complications of twin pregnancy after myomectomy. We aimed to compare the pregnancy outcomes in twin pregnancies with or without uterine fibroid(s), and also compared in patients with previous myomectomy history in Korean women. Methods A cohort of twin pregnancies delivered in a single institution between January 2011 and March 2019 were retrospectively analyzed. UFs group was defined by the presence of UFs during pregnancy (≥1 fibroid, measuring ≥2 cm or multiple fibroids regardless of the size). Previous myomectomy group included patients with history of abdominal or laparoscopic or hysteroscopic myomectomy of ≥1 fibroid, measuring ≥2 cm or multiple fibroids whatever the size. Patients with monochorionic monoamniotic twins, myoma less than 2 cm in size, missed abortion or intrauterine fetal death (IUFD) of one fetus before 14 weeks, history of previous conization, and uterine anomalies were excluded. Pregnancy outcomes and obstetric complications were compared. Result A total 1388 patients were included in this study, 191 (13.8%) had UFs and 89 (6.4%) had a history of myomectomy. Maternal age was younger in non-UFs group and primiparity was more common in UFs group (p < 0.001, and p = 0.019). No significant differences were found in the gestational age at delivery (p = 0.657), delivery before 37 weeks (p = 0.662), delivery before 34 weeks (p = 0.340), and sum of birth weight of twin (p = 0.307). There were also no statistical differences in rates of obstetrical complications, such as preeclampsia, gestational diabetes mellitus, placenta previa, placenta abruption, cerclage, small for gestational age, IUFD, postpartum hemorrhage and peripartum transfusion or ICU care. These obstetrical outcomes and complications showed no statistical differences between UFs group and previous myomectomy group. Conclusion In patients with twin pregnancies, the presence of UFs or history of previous myomectomy did not relate to negative effects on pregnancy outcomes and obstetrical complications.http://link.springer.com/article/10.1186/s12884-020-02908-wTwin pregnancyUterine fibroidPrevious myomectomyPreterm laborPreterm deliveryPregnancy outcome |
| spellingShingle | Mi-La Kim Kirim Hong Sohyun Kim Min Jin Lee Sung Shin Shim Yoon-Mi Hur Joong Sik Shin Twin pregnancies with uterine fibroids are not at increased risk for obstetric complications: single center cohort study BMC Pregnancy and Childbirth Twin pregnancy Uterine fibroid Previous myomectomy Preterm labor Preterm delivery Pregnancy outcome |
| title | Twin pregnancies with uterine fibroids are not at increased risk for obstetric complications: single center cohort study |
| title_full | Twin pregnancies with uterine fibroids are not at increased risk for obstetric complications: single center cohort study |
| title_fullStr | Twin pregnancies with uterine fibroids are not at increased risk for obstetric complications: single center cohort study |
| title_full_unstemmed | Twin pregnancies with uterine fibroids are not at increased risk for obstetric complications: single center cohort study |
| title_short | Twin pregnancies with uterine fibroids are not at increased risk for obstetric complications: single center cohort study |
| title_sort | twin pregnancies with uterine fibroids are not at increased risk for obstetric complications single center cohort study |
| topic | Twin pregnancy Uterine fibroid Previous myomectomy Preterm labor Preterm delivery Pregnancy outcome |
| url | http://link.springer.com/article/10.1186/s12884-020-02908-w |
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