Simultaneous measurement of tadehaginoside and its principal metabolite in rats by HPLC–MS/MS and its application in pharmacokinetics and tissue distribution study

Simultaneous measurement of tadehaginoside and its principal metabolite in rats by HPLC–MS/MS and its application in pharmacokinetics and tissue distribution study

Context Tadehaginoside, an active ingredient isolated from Tadehagi triquetrum (Linn.) Ohashi (Leguminosae), exhibited various biological activities. However, the pharmacokinetics and tissue distribution which affect tadehaginoside’s therapeutic actions and application remain elusive. Objective To c...

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Bibliographic Details
Main Authors: Cai-Yun Zhang, Ya-Ting Lu, Yin-Feng Tan, Qi-Bing Liu, Lin Dong, Ning Ma, Wei-Ying Lu, Zhi-Heng Su, Xiao-Po Zhang
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Pharmaceutical Biology
Subjects:
p-hydroxycinnamic
method development and validation
metabolic profile
Online Access:http://dx.doi.org/10.1080/13880209.2021.1990354

Internet

http://dx.doi.org/10.1080/13880209.2021.1990354

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