Chronic thromboembolic pulmonary hypertension is a clot you cannot swat

A 49-year-old man with progressive dyspnea on exertion and a remote history of syncope presented with hypotension and acute right ventricular failure, and was ultimately diagnosed with acute pulmonary embolism. Laboratory data revealed a prolonged activated partial thromboplastin time, which confoun...

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Main Authors: G. Jay Bishop, MD, FACP, FSVM, RPVI, Joshua Gorski, MD, Daniel Lachant, DO, Scott J. Cameron, MD, PhD, RPVI, FSVM, FACC
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Journal of Vascular Surgery Cases and Innovative Techniques
Online Access:http://www.sciencedirect.com/science/article/pii/S246842871930098X
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author G. Jay Bishop, MD, FACP, FSVM, RPVI
Joshua Gorski, MD
Daniel Lachant, DO
Scott J. Cameron, MD, PhD, RPVI, FSVM, FACC
author_facet G. Jay Bishop, MD, FACP, FSVM, RPVI
Joshua Gorski, MD
Daniel Lachant, DO
Scott J. Cameron, MD, PhD, RPVI, FSVM, FACC
author_sort G. Jay Bishop, MD, FACP, FSVM, RPVI
collection DOAJ
description A 49-year-old man with progressive dyspnea on exertion and a remote history of syncope presented with hypotension and acute right ventricular failure, and was ultimately diagnosed with acute pulmonary embolism. Laboratory data revealed a prolonged activated partial thromboplastin time, which confounded treatment options. He was ultimately diagnosed with anti-phospholipid syndrome and factor XII deficiency, and underwent a thromboendarterectomy procedure with resolution of right ventricular failure and symptoms. Careful attention to history, initial physical examination manifestations, and clinical data often permit a timely diagnosis of and treatment for chronic thromboembolic pulmonary hypertension. Keywords: Thrombus, Pulmonary embolism, Pulmonary hypertension, CTEPH
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spelling doaj.art-a52ab3344a4f497fbf067b10f28ae3af2022-12-21T23:48:51ZengElsevierJournal of Vascular Surgery Cases and Innovative Techniques2468-42872019-12-0154402405Chronic thromboembolic pulmonary hypertension is a clot you cannot swatG. Jay Bishop, MD, FACP, FSVM, RPVI0Joshua Gorski, MD1Daniel Lachant, DO2Scott J. Cameron, MD, PhD, RPVI, FSVM, FACC3UPMC Heart and Vascular Institute at UPMC Hamot, Erie, Pa; Department of Cardiovascular Medicine, Section of Vascular Medicine, Cleveland Clinic Foundation, Cleveland, OhioDepartment of Medicine, University of Rochester School of Medicine, Rochester, NYDivision of Pulmonary and Critical Care Medicine, Department of Medicine, University of Rochester School of Medicine, Rochester, NYDepartment of Cardiovascular Medicine, Section of Vascular Medicine, Cleveland Clinic Foundation, Cleveland, Ohio; Division of Cardiology, Department of Medicine, University of Rochester School of Medicine, Rochester, NY; Division of Cardiac Surgery, Department of Surgery, University of Rochester School of Medicine, Rochester, NY; Correspondence: Scott J. Cameron, MD, PhD, RPVI, FSVM, FACC, Cleveland Clinic Foundation, Department of Cardiovascular Medicine, Section of Vascular Medicine, J3-5, 9500 Euclid Ave, Cleveland, OH 44195A 49-year-old man with progressive dyspnea on exertion and a remote history of syncope presented with hypotension and acute right ventricular failure, and was ultimately diagnosed with acute pulmonary embolism. Laboratory data revealed a prolonged activated partial thromboplastin time, which confounded treatment options. He was ultimately diagnosed with anti-phospholipid syndrome and factor XII deficiency, and underwent a thromboendarterectomy procedure with resolution of right ventricular failure and symptoms. Careful attention to history, initial physical examination manifestations, and clinical data often permit a timely diagnosis of and treatment for chronic thromboembolic pulmonary hypertension. Keywords: Thrombus, Pulmonary embolism, Pulmonary hypertension, CTEPHhttp://www.sciencedirect.com/science/article/pii/S246842871930098X
spellingShingle G. Jay Bishop, MD, FACP, FSVM, RPVI
Joshua Gorski, MD
Daniel Lachant, DO
Scott J. Cameron, MD, PhD, RPVI, FSVM, FACC
Chronic thromboembolic pulmonary hypertension is a clot you cannot swat
Journal of Vascular Surgery Cases and Innovative Techniques
title Chronic thromboembolic pulmonary hypertension is a clot you cannot swat
title_full Chronic thromboembolic pulmonary hypertension is a clot you cannot swat
title_fullStr Chronic thromboembolic pulmonary hypertension is a clot you cannot swat
title_full_unstemmed Chronic thromboembolic pulmonary hypertension is a clot you cannot swat
title_short Chronic thromboembolic pulmonary hypertension is a clot you cannot swat
title_sort chronic thromboembolic pulmonary hypertension is a clot you cannot swat
url http://www.sciencedirect.com/science/article/pii/S246842871930098X
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