Recent Advances in Novel Lateral Flow Technologies for Detection of COVID-19
The development of reliable and robust diagnostic tests is one of the most efficient methods to limit the spread of coronavirus disease 2019 (COVID-19), which is caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). However, most laboratory diagnostics for COVID-19, such as enz...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-08-01
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| Series: | Biosensors |
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| Online Access: | https://www.mdpi.com/2079-6374/11/9/295 |
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| author | Wesley Wei-Wen Hsiao Trong-Nghia Le Dinh Minh Pham Hui-Hsin Ko Huan-Cheng Chang Cheng-Chung Lee Neha Sharma Cheng-Kang Lee Wei-Hung Chiang |
| author_facet | Wesley Wei-Wen Hsiao Trong-Nghia Le Dinh Minh Pham Hui-Hsin Ko Huan-Cheng Chang Cheng-Chung Lee Neha Sharma Cheng-Kang Lee Wei-Hung Chiang |
| author_sort | Wesley Wei-Wen Hsiao |
| collection | DOAJ |
| description | The development of reliable and robust diagnostic tests is one of the most efficient methods to limit the spread of coronavirus disease 2019 (COVID-19), which is caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). However, most laboratory diagnostics for COVID-19, such as enzyme-linked immunosorbent assay (ELISA) and reverse transcriptase-polymerase chain reaction (RT-PCR), are expensive, time-consuming, and require highly trained professional operators. On the other hand, the lateral flow immunoassay (LFIA) is a simpler, cheaper device that can be operated by unskilled personnel easily. Unfortunately, the current technique has some limitations, mainly inaccuracy in detection. This review article aims to highlight recent advances in novel lateral flow technologies for detecting SARS-CoV-2 as well as innovative approaches to achieve highly sensitive and specific point-of-care testing. Lastly, we discuss future perspectives on how smartphones and Artificial Intelligence (AI) can be integrated to revolutionize disease detection as well as disease control and surveillance. |
| first_indexed | 2024-03-10T07:51:30Z |
| format | Article |
| id | doaj.art-a537e546c28743689edcfa193c2a3a65 |
| institution | Directory Open Access Journal |
| issn | 2079-6374 |
| language | English |
| last_indexed | 2024-03-10T07:51:30Z |
| publishDate | 2021-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biosensors |
| spelling | doaj.art-a537e546c28743689edcfa193c2a3a652023-11-22T12:12:12ZengMDPI AGBiosensors2079-63742021-08-0111929510.3390/bios11090295Recent Advances in Novel Lateral Flow Technologies for Detection of COVID-19Wesley Wei-Wen Hsiao0Trong-Nghia Le1Dinh Minh Pham2Hui-Hsin Ko3Huan-Cheng Chang4Cheng-Chung Lee5Neha Sharma6Cheng-Kang Lee7Wei-Hung Chiang8Department of Chemical Engineering, National Taiwan University of Science and Technology, Taipei 106, TaiwanDepartment of Chemical Engineering, National Taiwan University of Science and Technology, Taipei 106, TaiwanGENTIS JSC, 249A, Thuy Khue, Tay Ho, Hanoi 100000, VietnamInstitute of Biological Chemistry, Academia Sinica, Taipei 115, TaiwanDepartment of Chemical Engineering, National Taiwan University of Science and Technology, Taipei 106, TaiwanInstitute of Biological Chemistry, Academia Sinica, Taipei 115, TaiwanDepartment of Chemical Engineering, National Taiwan University of Science and Technology, Taipei 106, TaiwanDepartment of Chemical Engineering, National Taiwan University of Science and Technology, Taipei 106, TaiwanDepartment of Chemical Engineering, National Taiwan University of Science and Technology, Taipei 106, TaiwanThe development of reliable and robust diagnostic tests is one of the most efficient methods to limit the spread of coronavirus disease 2019 (COVID-19), which is caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). However, most laboratory diagnostics for COVID-19, such as enzyme-linked immunosorbent assay (ELISA) and reverse transcriptase-polymerase chain reaction (RT-PCR), are expensive, time-consuming, and require highly trained professional operators. On the other hand, the lateral flow immunoassay (LFIA) is a simpler, cheaper device that can be operated by unskilled personnel easily. Unfortunately, the current technique has some limitations, mainly inaccuracy in detection. This review article aims to highlight recent advances in novel lateral flow technologies for detecting SARS-CoV-2 as well as innovative approaches to achieve highly sensitive and specific point-of-care testing. Lastly, we discuss future perspectives on how smartphones and Artificial Intelligence (AI) can be integrated to revolutionize disease detection as well as disease control and surveillance.https://www.mdpi.com/2079-6374/11/9/295COVID-19SARS-CoV-2lateral flow assaypoint-of-care testingartificial intelligence |
| spellingShingle | Wesley Wei-Wen Hsiao Trong-Nghia Le Dinh Minh Pham Hui-Hsin Ko Huan-Cheng Chang Cheng-Chung Lee Neha Sharma Cheng-Kang Lee Wei-Hung Chiang Recent Advances in Novel Lateral Flow Technologies for Detection of COVID-19 Biosensors COVID-19 SARS-CoV-2 lateral flow assay point-of-care testing artificial intelligence |
| title | Recent Advances in Novel Lateral Flow Technologies for Detection of COVID-19 |
| title_full | Recent Advances in Novel Lateral Flow Technologies for Detection of COVID-19 |
| title_fullStr | Recent Advances in Novel Lateral Flow Technologies for Detection of COVID-19 |
| title_full_unstemmed | Recent Advances in Novel Lateral Flow Technologies for Detection of COVID-19 |
| title_short | Recent Advances in Novel Lateral Flow Technologies for Detection of COVID-19 |
| title_sort | recent advances in novel lateral flow technologies for detection of covid 19 |
| topic | COVID-19 SARS-CoV-2 lateral flow assay point-of-care testing artificial intelligence |
| url | https://www.mdpi.com/2079-6374/11/9/295 |
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