Protective role of the alpha-1-antitrypsin in intervertebral disc degeneration
Abstract Background Intervertebral disc degeneration is a complex disease with high prevalence. It suggests that cell death, senescence, and extracellular matrix degradation are involved in the pathogenesis. Alpha-1 antitrypsin (AAT), a serine protease inhibitor, was previously correlated with infla...
Main Authors: | Weikun Liu, Yanfu Wang |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-08-01
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Series: | Journal of Orthopaedic Surgery and Research |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13018-021-02668-z |
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