The protective role of Pomegranate seed oil (Pometone) on serum protein in sodium fluoride treated female rats

This study is designed to determin the protective role of pomegranate seed oil against deleterious effect induced by sodium fluoride on serum proteins in rats. Forty (40) adult female rats were randomly divided into four equal group (10/group) and treated daily for 40 days as following: Group C admi...

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Main Author: Baraa Najim Al-Okaily
Format: Article
Language:English
Published: University of Baghdad, College of Veterinary Medicine 2016-06-01
Series:The Iraqi Journal of Veterinary Medicine
Subjects:
Online Access:https://jcovm.uobaghdad.edu.iq/index.php/Iraqijvm/article/view/139
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author Baraa Najim Al-Okaily
author_facet Baraa Najim Al-Okaily
author_sort Baraa Najim Al-Okaily
collection DOAJ
description This study is designed to determin the protective role of pomegranate seed oil against deleterious effect induced by sodium fluoride on serum proteins in rats. Forty (40) adult female rats were randomly divided into four equal group (10/group) and treated daily for 40 days as following: Group C administered distilled water (control), group T1 received sodium fluoride 120 ppm/liter in drinking water, group T2 received both sodium fluoride 120 ppm/liter in drinking water and Pometone 30 mg/kg B.w. orally and group T3 administered Pometone 30 mg/kg B.w. orally. Fasting blood samples were collected at 0, 20 and 40 days of the experimental periods and serum samples were aliquoted for estimation serum total protein, albumin and globulin concentrations. Also, protein electrophoresis was measured. The results revealed that sodium fluoride caused significant reduction in serum total protein, albumin and globulin concentrations, in addition to changes in the patterns of serum protein fractions % (albumin, α1-globulin, α2-globulin, β-globulin and γ-globulin) as compared with control rats. In conclusion Pomegranate seed oil caused elevation of proteins concentration as compared to group T1 and could potentially be beneficial in preventing the hepatic damage caused by sodium fluoride.
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spelling doaj.art-a53955e41c63407d8fa526c0c4ab4cdc2022-12-21T20:07:24ZengUniversity of Baghdad, College of Veterinary MedicineThe Iraqi Journal of Veterinary Medicine1609-56932410-74092016-06-0140110.30539/iraqijvm.v40i1.139The protective role of Pomegranate seed oil (Pometone) on serum protein in sodium fluoride treated female ratsBaraa Najim Al-Okaily0, College of Veterinary Medicine, University of BaghdadThis study is designed to determin the protective role of pomegranate seed oil against deleterious effect induced by sodium fluoride on serum proteins in rats. Forty (40) adult female rats were randomly divided into four equal group (10/group) and treated daily for 40 days as following: Group C administered distilled water (control), group T1 received sodium fluoride 120 ppm/liter in drinking water, group T2 received both sodium fluoride 120 ppm/liter in drinking water and Pometone 30 mg/kg B.w. orally and group T3 administered Pometone 30 mg/kg B.w. orally. Fasting blood samples were collected at 0, 20 and 40 days of the experimental periods and serum samples were aliquoted for estimation serum total protein, albumin and globulin concentrations. Also, protein electrophoresis was measured. The results revealed that sodium fluoride caused significant reduction in serum total protein, albumin and globulin concentrations, in addition to changes in the patterns of serum protein fractions % (albumin, α1-globulin, α2-globulin, β-globulin and γ-globulin) as compared with control rats. In conclusion Pomegranate seed oil caused elevation of proteins concentration as compared to group T1 and could potentially be beneficial in preventing the hepatic damage caused by sodium fluoride.https://jcovm.uobaghdad.edu.iq/index.php/Iraqijvm/article/view/139Pomegranate seed oil, Sodium fluoride, Total protein, Protein electrophoresis, Rats.
spellingShingle Baraa Najim Al-Okaily
The protective role of Pomegranate seed oil (Pometone) on serum protein in sodium fluoride treated female rats
The Iraqi Journal of Veterinary Medicine
Pomegranate seed oil, Sodium fluoride, Total protein, Protein electrophoresis, Rats.
title The protective role of Pomegranate seed oil (Pometone) on serum protein in sodium fluoride treated female rats
title_full The protective role of Pomegranate seed oil (Pometone) on serum protein in sodium fluoride treated female rats
title_fullStr The protective role of Pomegranate seed oil (Pometone) on serum protein in sodium fluoride treated female rats
title_full_unstemmed The protective role of Pomegranate seed oil (Pometone) on serum protein in sodium fluoride treated female rats
title_short The protective role of Pomegranate seed oil (Pometone) on serum protein in sodium fluoride treated female rats
title_sort protective role of pomegranate seed oil pometone on serum protein in sodium fluoride treated female rats
topic Pomegranate seed oil, Sodium fluoride, Total protein, Protein electrophoresis, Rats.
url https://jcovm.uobaghdad.edu.iq/index.php/Iraqijvm/article/view/139
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