The protective role of Pomegranate seed oil (Pometone) on serum protein in sodium fluoride treated female rats
This study is designed to determin the protective role of pomegranate seed oil against deleterious effect induced by sodium fluoride on serum proteins in rats. Forty (40) adult female rats were randomly divided into four equal group (10/group) and treated daily for 40 days as following: Group C admi...
Main Author: | |
---|---|
Format: | Article |
Language: | English |
Published: |
University of Baghdad, College of Veterinary Medicine
2016-06-01
|
Series: | The Iraqi Journal of Veterinary Medicine |
Subjects: | |
Online Access: | https://jcovm.uobaghdad.edu.iq/index.php/Iraqijvm/article/view/139 |
_version_ | 1818900734938185728 |
---|---|
author | Baraa Najim Al-Okaily |
author_facet | Baraa Najim Al-Okaily |
author_sort | Baraa Najim Al-Okaily |
collection | DOAJ |
description | This study is designed to determin the protective role of pomegranate seed oil against deleterious effect induced by sodium fluoride on serum proteins in rats. Forty (40) adult female rats were randomly divided into four equal group (10/group) and treated daily for 40 days as following: Group C administered distilled water (control), group T1 received sodium fluoride 120 ppm/liter in drinking water, group T2 received both sodium fluoride 120 ppm/liter in drinking water and Pometone 30 mg/kg B.w. orally and group T3 administered Pometone 30 mg/kg B.w. orally. Fasting blood samples were collected at 0, 20 and 40 days of the experimental periods and serum samples were aliquoted for estimation serum total protein, albumin and globulin concentrations. Also, protein electrophoresis was measured. The results revealed that sodium fluoride caused significant reduction in serum total protein, albumin and globulin concentrations, in addition to changes in the patterns of serum protein fractions % (albumin, α1-globulin, α2-globulin, β-globulin and γ-globulin) as compared with control rats. In conclusion Pomegranate seed oil caused elevation of proteins concentration as compared to group T1 and could potentially be beneficial in preventing the hepatic damage caused by sodium fluoride. |
first_indexed | 2024-12-19T20:08:34Z |
format | Article |
id | doaj.art-a53955e41c63407d8fa526c0c4ab4cdc |
institution | Directory Open Access Journal |
issn | 1609-5693 2410-7409 |
language | English |
last_indexed | 2024-12-19T20:08:34Z |
publishDate | 2016-06-01 |
publisher | University of Baghdad, College of Veterinary Medicine |
record_format | Article |
series | The Iraqi Journal of Veterinary Medicine |
spelling | doaj.art-a53955e41c63407d8fa526c0c4ab4cdc2022-12-21T20:07:24ZengUniversity of Baghdad, College of Veterinary MedicineThe Iraqi Journal of Veterinary Medicine1609-56932410-74092016-06-0140110.30539/iraqijvm.v40i1.139The protective role of Pomegranate seed oil (Pometone) on serum protein in sodium fluoride treated female ratsBaraa Najim Al-Okaily0, College of Veterinary Medicine, University of BaghdadThis study is designed to determin the protective role of pomegranate seed oil against deleterious effect induced by sodium fluoride on serum proteins in rats. Forty (40) adult female rats were randomly divided into four equal group (10/group) and treated daily for 40 days as following: Group C administered distilled water (control), group T1 received sodium fluoride 120 ppm/liter in drinking water, group T2 received both sodium fluoride 120 ppm/liter in drinking water and Pometone 30 mg/kg B.w. orally and group T3 administered Pometone 30 mg/kg B.w. orally. Fasting blood samples were collected at 0, 20 and 40 days of the experimental periods and serum samples were aliquoted for estimation serum total protein, albumin and globulin concentrations. Also, protein electrophoresis was measured. The results revealed that sodium fluoride caused significant reduction in serum total protein, albumin and globulin concentrations, in addition to changes in the patterns of serum protein fractions % (albumin, α1-globulin, α2-globulin, β-globulin and γ-globulin) as compared with control rats. In conclusion Pomegranate seed oil caused elevation of proteins concentration as compared to group T1 and could potentially be beneficial in preventing the hepatic damage caused by sodium fluoride.https://jcovm.uobaghdad.edu.iq/index.php/Iraqijvm/article/view/139Pomegranate seed oil, Sodium fluoride, Total protein, Protein electrophoresis, Rats. |
spellingShingle | Baraa Najim Al-Okaily The protective role of Pomegranate seed oil (Pometone) on serum protein in sodium fluoride treated female rats The Iraqi Journal of Veterinary Medicine Pomegranate seed oil, Sodium fluoride, Total protein, Protein electrophoresis, Rats. |
title | The protective role of Pomegranate seed oil (Pometone) on serum protein in sodium fluoride treated female rats |
title_full | The protective role of Pomegranate seed oil (Pometone) on serum protein in sodium fluoride treated female rats |
title_fullStr | The protective role of Pomegranate seed oil (Pometone) on serum protein in sodium fluoride treated female rats |
title_full_unstemmed | The protective role of Pomegranate seed oil (Pometone) on serum protein in sodium fluoride treated female rats |
title_short | The protective role of Pomegranate seed oil (Pometone) on serum protein in sodium fluoride treated female rats |
title_sort | protective role of pomegranate seed oil pometone on serum protein in sodium fluoride treated female rats |
topic | Pomegranate seed oil, Sodium fluoride, Total protein, Protein electrophoresis, Rats. |
url | https://jcovm.uobaghdad.edu.iq/index.php/Iraqijvm/article/view/139 |
work_keys_str_mv | AT baraanajimalokaily theprotectiveroleofpomegranateseedoilpometoneonserumproteininsodiumfluoridetreatedfemalerats AT baraanajimalokaily protectiveroleofpomegranateseedoilpometoneonserumproteininsodiumfluoridetreatedfemalerats |