Correlation between human gut microbiome and diseases
Human gut microbiome is a major source of human bacterial population and a significant contribution to both positive and harmful effects. Due to its involvement in a variety of interactions, gut microorganisms have a great impact on our health throughout our lives. The impact of gut microbial popula...
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| Format: | Article |
| Language: | English |
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Elsevier
2022-09-01
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| Series: | Infectious Medicine |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772431X22000375 |
| _version_ | 1797345865516449792 |
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| author | Barkha Madhogaria Priyanka Bhowmik Atreyee Kundu |
| author_facet | Barkha Madhogaria Priyanka Bhowmik Atreyee Kundu |
| author_sort | Barkha Madhogaria |
| collection | DOAJ |
| description | Human gut microbiome is a major source of human bacterial population and a significant contribution to both positive and harmful effects. Due to its involvement in a variety of interactions, gut microorganisms have a great impact on our health throughout our lives. The impact of gut microbial population is been studied intensively in last two decades. Extensive literature survey focusing developments in the field were searched in English language Electronic Databases like PubMed, Google Scholar, Pubag, Google books, and Research Gate were mostly used to understand the role of human gut mirobiome and its role in different human diseases. Gut microbiome in healthy subjects differs from those who suffer from diseases. Type 2 diabetes, obesity, non-alcoholic liver disease, and cardiometabolic diseases have all been linked to dysbiosis of the gut microbiota. Pathogenesis of many disorders is also linked to changes in gut microbiota. Other diseases like cancer, arithritis, autism, depression, anxiety, sleep disorder, HIV, hypertension, and gout are also related to gut microbiota dysbiosis. We focus in this review on recent studies looking into the link between gut microbiome dysbiosis and disease etiology. Research on how gut microbiota affects host metabolism has been changed in past decades from descriptive analyses to high throughput integrative omics data analysis such as metagenomics and metabolomics. Identification of molecular mechanisms behind reported associations is been carried out in human, animals, and cells for measure of host physiology and mechanics. Still many the mechanisms are not completely understood. |
| first_indexed | 2024-03-08T11:24:55Z |
| format | Article |
| id | doaj.art-a539a7b3a1d64a6fa548c6232b7f5126 |
| institution | Directory Open Access Journal |
| issn | 2772-431X |
| language | English |
| last_indexed | 2024-03-08T11:24:55Z |
| publishDate | 2022-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Infectious Medicine |
| spelling | doaj.art-a539a7b3a1d64a6fa548c6232b7f51262024-01-26T05:36:03ZengElsevierInfectious Medicine2772-431X2022-09-0113180191Correlation between human gut microbiome and diseasesBarkha Madhogaria0Priyanka Bhowmik1Atreyee Kundu2Department of Microbiology, Techno India University, West Bengal EM-4 Sector-V, Salt Lake City, Kolkata 700091, West Bengal, IndiaDepartment of Biological Sciences, Adamas University, Barrackpore-Barasat Road, 24 Paragnas North, Jagannathpur, Kolkata, West Bengal, India; Corresponding authors: P. Bhowmik and A. KunduDepartment of Microbiology, Techno India University, West Bengal EM-4 Sector-V, Salt Lake City, Kolkata 700091, West Bengal, India; Corresponding authors: P. Bhowmik and A. KunduHuman gut microbiome is a major source of human bacterial population and a significant contribution to both positive and harmful effects. Due to its involvement in a variety of interactions, gut microorganisms have a great impact on our health throughout our lives. The impact of gut microbial population is been studied intensively in last two decades. Extensive literature survey focusing developments in the field were searched in English language Electronic Databases like PubMed, Google Scholar, Pubag, Google books, and Research Gate were mostly used to understand the role of human gut mirobiome and its role in different human diseases. Gut microbiome in healthy subjects differs from those who suffer from diseases. Type 2 diabetes, obesity, non-alcoholic liver disease, and cardiometabolic diseases have all been linked to dysbiosis of the gut microbiota. Pathogenesis of many disorders is also linked to changes in gut microbiota. Other diseases like cancer, arithritis, autism, depression, anxiety, sleep disorder, HIV, hypertension, and gout are also related to gut microbiota dysbiosis. We focus in this review on recent studies looking into the link between gut microbiome dysbiosis and disease etiology. Research on how gut microbiota affects host metabolism has been changed in past decades from descriptive analyses to high throughput integrative omics data analysis such as metagenomics and metabolomics. Identification of molecular mechanisms behind reported associations is been carried out in human, animals, and cells for measure of host physiology and mechanics. Still many the mechanisms are not completely understood.http://www.sciencedirect.com/science/article/pii/S2772431X22000375BacteriaGutInfectionsMicrobiomeMicrobiotaMicroflora |
| spellingShingle | Barkha Madhogaria Priyanka Bhowmik Atreyee Kundu Correlation between human gut microbiome and diseases Infectious Medicine Bacteria Gut Infections Microbiome Microbiota Microflora |
| title | Correlation between human gut microbiome and diseases |
| title_full | Correlation between human gut microbiome and diseases |
| title_fullStr | Correlation between human gut microbiome and diseases |
| title_full_unstemmed | Correlation between human gut microbiome and diseases |
| title_short | Correlation between human gut microbiome and diseases |
| title_sort | correlation between human gut microbiome and diseases |
| topic | Bacteria Gut Infections Microbiome Microbiota Microflora |
| url | http://www.sciencedirect.com/science/article/pii/S2772431X22000375 |
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