Mechanical Unloading of Engineered Human Meniscus Models Under Simulated Microgravity: A Transcriptomic Study

Abstract Osteoarthritis (OA) primarily affects mechanical load-bearing joints, with the knee being the most common. The prevalence, burden and severity of knee osteoarthritis (KOA) are disproportionately higher in females, but hormonal differences alone do not explain the disproportionate incidence...

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Bibliographic Details
Main Authors: Zhiyao Ma, David Xinzheyang Li, Ryan K. W. Chee, Melanie Kunze, Aillette Mulet-Sierra, Mark Sommerfeldt, Lindsey Westover, Daniel Graf, Adetola B. Adesida
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Scientific Data
Online Access:https://doi.org/10.1038/s41597-022-01837-x