Parvimonas micra, an oral pathobiont associated with colorectal cancer, epigenetically reprograms human colonocytes

Parvimonas micra, an oral pathobiont associated with colorectal cancer, epigenetically reprograms human colonocytes

ABSTRACTRecently, an intestinal dysbiotic microbiota with enrichment in oral cavity bacteria has been described in colorectal cancer (CRC) patients. Here, we characterize and investigate one of these oral pathobionts, the Gram-positive anaerobic coccus Parvimonas micra. We identified two phylotypes...

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Bibliographic Details
Main Authors: Emma Bergsten, Denis Mestivier, Francoise Donnadieu, Thierry Pedron, Caroline Barau, Landry Tsoumtsa Meda, Amel Mettouchi, Emmanuel Lemichez, Olivier Gorgette, Mathias Chamaillard, Amaury Vaysse, Stevenn Volant, Abiba Doukani, Philippe J. Sansonetti, Iradj Sobhani, Giulia Nigro
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Gut Microbes
Subjects:
Colorectal cancer
colonic epithelial primary cells
pathobionts
Parvimonas micra
DNA methylation
Online Access:https://www.tandfonline.com/doi/10.1080/19490976.2023.2265138

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