DNA methylation and single nucleotide variants in the brain-derived neurotrophic factor (BDNF) and oxytocin receptor (OXTR) genes are associated with anxiety/depression in older women

DNA methylation and single nucleotide variants in the brain-derived neurotrophic factor (BDNF) and oxytocin receptor (OXTR) genes are associated with anxiety/depression in older women

Background: Environmental effects and personal experiences could be expressed in individuals through epigenetic non-structural changes such as DNA methylation. This methylation could up- regulate or down-regulate corresponding gene expressions and modify related phenotypes. DNA methylation increases...

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Bibliographic Details
Main Authors: Yvon eChagnon, Olivier ePotvin, Carol eHudon, Michel ePreville
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-06-01
Series:Frontiers in Genetics
Subjects:
Aging
Anxiety
Methylation
snps
OXTR
BDNF Val66Met
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00230/full

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