A click chemistry amplified nanopore assay for ultrasensitive quantification of HIV-1 p24 antigen in clinical samples
Accurate detection of antigen p24 for HIV−1 early diagnosis remains challenging. Here the authors present a click chemistry amplified nanopore (CAN) assay that allows p24 quantification at ultralow concentration range in clinical samples.
Main Authors: | Xiaojun Wei, Xiaoqin Wang, Zehui Zhang, Yuanyuan Luo, Zixin Wang, Wen Xiong, Piyush K. Jain, John R. Monnier, Hui Wang, Tony Y. Hu, Chuanbing Tang, Helmut Albrecht, Chang Liu |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-11-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-022-34273-x |
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