Generation and characterization of induced pluripotent stem cells from a Parkinson’s disease patient carrying the digenic LRRK2 p.G2019S and GBA1 p.N409S mutations
We describe an induced pluripotent stem cell (iPSC) line that was derived from fibroblasts obtained from a Parkinson’s disease (PD) patient carrying the p.G2019S mutation in the LRRK2 gene and the p.N409S mutation in the GBA1 gene. iPSCs were generated via Sendai virus transduction of Yamanaka facto...
Главные авторы: | Christiane Oleksy, François Massart, Stefano Goldwurm, Alessia Arado, Giuseppe Arena, Ibrahim Boussaad, Rejko Krüger |
---|---|
Формат: | Статья |
Язык: | English |
Опубликовано: |
Elsevier
2023-10-01
|
Серии: | Stem Cell Research |
Online-ссылка: | http://www.sciencedirect.com/science/article/pii/S1873506123001988 |
Схожие документы
-
The Effect of p.G2019S Mutation in the LRRK2 Gene on the Activity of Lysosomal Hydrolases and the Clinical Features of Parkinson's Disease Associated with p.N370S Mutation in the GBA1 Gene
по: Tatiana S. Usenko, и др.
Опубликовано: (2024-01-01) -
Generation of an induced pluripotent stem cell line (CSC-41) from a Parkinson's disease patient carrying a p.G2019S mutation in the LRRK2 gene
по: Ana Marote, и др.
Опубликовано: (2018-04-01) -
Detection of ER Stress in iPSC-Derived Neurons Carrying the p.N370S Mutation in the <i>GBA1</i> Gene
по: Elena S. Yarkova, и др.
Опубликовано: (2024-03-01) -
GBA mutations p.N370S and p.L444P are associated with Parkinson's disease in patients from Northern Brazil
по: Carlos Eduardo de Melo Amaral, и др. -
<it>LRRK2 </it>in Parkinson's disease – drawing the curtain of penetrance: a commentary
по: Krüger Rejko
Опубликовано: (2008-11-01)