Scavenging Capacity of Extracts of <i>Arrabidaea chica</i> Leaves from the Amazonia against ROS and RNS of Physiological and Food Relevance
<i>Arrabidaea chica</i>, a medicinal plant found in the Amazon rainforest, is a promising source of bioactive compounds which can be used to inhibit oxidative damage in both food and biological systems. In this study, the in vitro scavenging capacity of characterized extracts of <i>...
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| Format: | Article |
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MDPI AG
2022-09-01
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| Series: | Antioxidants |
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| Online Access: | https://www.mdpi.com/2076-3921/11/10/1909 |
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| author | Francilia Campos de Siqueira Anna Paula Pereira Barbosa-Carvalho Deusa do Socorro Teixeira Costa Leitão Kalebe Ferreira Furtado Gilson Celso Albuquerque Chagas-Junior Alessandra Santos Lopes Renan Campos Chisté |
| author_facet | Francilia Campos de Siqueira Anna Paula Pereira Barbosa-Carvalho Deusa do Socorro Teixeira Costa Leitão Kalebe Ferreira Furtado Gilson Celso Albuquerque Chagas-Junior Alessandra Santos Lopes Renan Campos Chisté |
| author_sort | Francilia Campos de Siqueira |
| collection | DOAJ |
| description | <i>Arrabidaea chica</i>, a medicinal plant found in the Amazon rainforest, is a promising source of bioactive compounds which can be used to inhibit oxidative damage in both food and biological systems. In this study, the in vitro scavenging capacity of characterized extracts of <i>A. chica</i> leaves, obtained with green solvents of different polarities [water, ethanol, and ethanol/water (1:1, <i>v</i>/<i>v</i>)] through ultrasound-assisted extraction, was investigated against reactive oxygen (ROS) and nitrogen (RNS) species, namely superoxide anion radicals (O<sub>2</sub><sup>•</sup><sup>−</sup>), hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>), hypochlorous acid (HOCl), and peroxynitrite anion (ONOO<sup>−</sup>). The extract obtained with ethanol–water presented about three times more phenolic compound contents (11.8 mg/g) than ethanol and water extracts (3.8 and 3.6 mg/g, respectively), with scutellarein being the major compound (6.76 mg/g). All extracts showed high scavenging efficiency against the tested ROS and RNS, in a concentration-dependent manner with low IC<sub>50</sub> values, and the ethanol–water extract was the most effective one. In addition, all the extracts were five times more efficient against ROO<sup>•</sup> than Trolox. Therefore, the extracts from <i>A. chica</i> leaves exhibited high promising antioxidant potential to be used against oxidative damage in food and physiological systems. |
| first_indexed | 2024-03-09T20:49:46Z |
| format | Article |
| id | doaj.art-a540413e6d6e428a91b1a36ce1bb48fd |
| institution | Directory Open Access Journal |
| issn | 2076-3921 |
| language | English |
| last_indexed | 2024-03-09T20:49:46Z |
| publishDate | 2022-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antioxidants |
| spelling | doaj.art-a540413e6d6e428a91b1a36ce1bb48fd2023-11-23T22:37:46ZengMDPI AGAntioxidants2076-39212022-09-011110190910.3390/antiox11101909Scavenging Capacity of Extracts of <i>Arrabidaea chica</i> Leaves from the Amazonia against ROS and RNS of Physiological and Food RelevanceFrancilia Campos de Siqueira0Anna Paula Pereira Barbosa-Carvalho1Deusa do Socorro Teixeira Costa Leitão2Kalebe Ferreira Furtado3Gilson Celso Albuquerque Chagas-Junior4Alessandra Santos Lopes5Renan Campos Chisté6Graduate Program of Food Science and Technology, Institute of Technology, Federal University of Pará (UFPA), Belém 66075-110, BrazilGraduate Program of Food Science and Technology, Institute of Technology, Federal University of Pará (UFPA), Belém 66075-110, BrazilGraduate Program of Food Science and Technology, Institute of Technology, Federal University of Pará (UFPA), Belém 66075-110, BrazilSchool of Biotechnology, Institute of Biological Sciences (ICB), Federal University of Pará (UFPA), Belém 66075-110, BrazilGraduate Program of Food Science and Technology, Institute of Technology, Federal University of Pará (UFPA), Belém 66075-110, BrazilGraduate Program of Food Science and Technology, Institute of Technology, Federal University of Pará (UFPA), Belém 66075-110, BrazilGraduate Program of Food Science and Technology, Institute of Technology, Federal University of Pará (UFPA), Belém 66075-110, Brazil<i>Arrabidaea chica</i>, a medicinal plant found in the Amazon rainforest, is a promising source of bioactive compounds which can be used to inhibit oxidative damage in both food and biological systems. In this study, the in vitro scavenging capacity of characterized extracts of <i>A. chica</i> leaves, obtained with green solvents of different polarities [water, ethanol, and ethanol/water (1:1, <i>v</i>/<i>v</i>)] through ultrasound-assisted extraction, was investigated against reactive oxygen (ROS) and nitrogen (RNS) species, namely superoxide anion radicals (O<sub>2</sub><sup>•</sup><sup>−</sup>), hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>), hypochlorous acid (HOCl), and peroxynitrite anion (ONOO<sup>−</sup>). The extract obtained with ethanol–water presented about three times more phenolic compound contents (11.8 mg/g) than ethanol and water extracts (3.8 and 3.6 mg/g, respectively), with scutellarein being the major compound (6.76 mg/g). All extracts showed high scavenging efficiency against the tested ROS and RNS, in a concentration-dependent manner with low IC<sub>50</sub> values, and the ethanol–water extract was the most effective one. In addition, all the extracts were five times more efficient against ROO<sup>•</sup> than Trolox. Therefore, the extracts from <i>A. chica</i> leaves exhibited high promising antioxidant potential to be used against oxidative damage in food and physiological systems.https://www.mdpi.com/2076-3921/11/10/1909antioxidant capacityAmazonian plantreactive oxygen speciesreactive nitrogen speciesgreen solventsphenolic compounds |
| spellingShingle | Francilia Campos de Siqueira Anna Paula Pereira Barbosa-Carvalho Deusa do Socorro Teixeira Costa Leitão Kalebe Ferreira Furtado Gilson Celso Albuquerque Chagas-Junior Alessandra Santos Lopes Renan Campos Chisté Scavenging Capacity of Extracts of <i>Arrabidaea chica</i> Leaves from the Amazonia against ROS and RNS of Physiological and Food Relevance Antioxidants antioxidant capacity Amazonian plant reactive oxygen species reactive nitrogen species green solvents phenolic compounds |
| title | Scavenging Capacity of Extracts of <i>Arrabidaea chica</i> Leaves from the Amazonia against ROS and RNS of Physiological and Food Relevance |
| title_full | Scavenging Capacity of Extracts of <i>Arrabidaea chica</i> Leaves from the Amazonia against ROS and RNS of Physiological and Food Relevance |
| title_fullStr | Scavenging Capacity of Extracts of <i>Arrabidaea chica</i> Leaves from the Amazonia against ROS and RNS of Physiological and Food Relevance |
| title_full_unstemmed | Scavenging Capacity of Extracts of <i>Arrabidaea chica</i> Leaves from the Amazonia against ROS and RNS of Physiological and Food Relevance |
| title_short | Scavenging Capacity of Extracts of <i>Arrabidaea chica</i> Leaves from the Amazonia against ROS and RNS of Physiological and Food Relevance |
| title_sort | scavenging capacity of extracts of i arrabidaea chica i leaves from the amazonia against ros and rns of physiological and food relevance |
| topic | antioxidant capacity Amazonian plant reactive oxygen species reactive nitrogen species green solvents phenolic compounds |
| url | https://www.mdpi.com/2076-3921/11/10/1909 |
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