Factors Associated with Medication Non-Adherence in Patients with Dyslipidemia

Lack of medication adherence among patients with dyslipidemia negatively affects health-related outcomes. This study aims to evaluate medication adherence; we also aim to investigate the predictors of non-adherence among patients with dyslipidemia in Jordan. Medication adherence was evaluated in a t...

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Main Authors: Eman Alefishat, Anan S. Jarab, Walid Al-Qerem, Lina Abu-Zaytoun
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Healthcare
Subjects:
Online Access:https://www.mdpi.com/2227-9032/9/7/813
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author Eman Alefishat
Anan S. Jarab
Walid Al-Qerem
Lina Abu-Zaytoun
author_facet Eman Alefishat
Anan S. Jarab
Walid Al-Qerem
Lina Abu-Zaytoun
author_sort Eman Alefishat
collection DOAJ
description Lack of medication adherence among patients with dyslipidemia negatively affects health-related outcomes. This study aims to evaluate medication adherence; we also aim to investigate the predictors of non-adherence among patients with dyslipidemia in Jordan. Medication adherence was evaluated in a total of 228 dyslipidemia patients. The Beliefs about Medicines Questionnaire was also used to assess patients’ beliefs about medications. The majority of the current study participants (73.2%) reported non-adherence to the prescribed medications. There were significant negative associations between medication adherence and concerns of prescription drug use (B = −0.41, <i>p</i>-value < 0.01), duration of dyslipidemia (B = −0.22, <i>p</i>-value < 0.01), and the number of medications (B = −0.64, <i>p</i>-value < 0.01). Positive associations were found between medication adherence and the necessity of prescription drug use (B = 0.43, <i>p</i>-value < 0.01), taking statin and fibrate (B = 2.04, <i>p</i>-value < 0.01), and moderate-intensity statin (B = 2.34, <i>p</i>-value < 0.01). As for patients’ beliefs about medications, the item “My medicine to lower my cholesterol disrupted my life” had the highest mean (3.50 ± 0.99). This study revealed a low adherence rate to medication among patients with dyslipidemia. It also demonstrates modifiable factors such as beliefs regarding perceived risk, medication harms, treatment duration, and the number of medications associated with poor adherence in patients with dyslipidemia.
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spelling doaj.art-a5426ff506904e998e4af821b767a1352023-11-22T02:00:40ZengMDPI AGHealthcare2227-90322021-06-019781310.3390/healthcare9070813Factors Associated with Medication Non-Adherence in Patients with DyslipidemiaEman Alefishat0Anan S. Jarab1Walid Al-Qerem2Lina Abu-Zaytoun3Department of Pharmacology, College of Medicine and Health Science, Khalifa University of Science and Technology, Abu Dhabi 127788, United Arab EmiratesDepartment of Clinical Pharmacy, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid 22110, JordanDepartment of Pharmacy, Faculty of Pharmacy, Al-Zaytoonah University of Jordan, Amman 11733, JordanDepartment of Clinical Pharmacy, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid 22110, JordanLack of medication adherence among patients with dyslipidemia negatively affects health-related outcomes. This study aims to evaluate medication adherence; we also aim to investigate the predictors of non-adherence among patients with dyslipidemia in Jordan. Medication adherence was evaluated in a total of 228 dyslipidemia patients. The Beliefs about Medicines Questionnaire was also used to assess patients’ beliefs about medications. The majority of the current study participants (73.2%) reported non-adherence to the prescribed medications. There were significant negative associations between medication adherence and concerns of prescription drug use (B = −0.41, <i>p</i>-value < 0.01), duration of dyslipidemia (B = −0.22, <i>p</i>-value < 0.01), and the number of medications (B = −0.64, <i>p</i>-value < 0.01). Positive associations were found between medication adherence and the necessity of prescription drug use (B = 0.43, <i>p</i>-value < 0.01), taking statin and fibrate (B = 2.04, <i>p</i>-value < 0.01), and moderate-intensity statin (B = 2.34, <i>p</i>-value < 0.01). As for patients’ beliefs about medications, the item “My medicine to lower my cholesterol disrupted my life” had the highest mean (3.50 ± 0.99). This study revealed a low adherence rate to medication among patients with dyslipidemia. It also demonstrates modifiable factors such as beliefs regarding perceived risk, medication harms, treatment duration, and the number of medications associated with poor adherence in patients with dyslipidemia.https://www.mdpi.com/2227-9032/9/7/813adherencedyslipidemiastatin
spellingShingle Eman Alefishat
Anan S. Jarab
Walid Al-Qerem
Lina Abu-Zaytoun
Factors Associated with Medication Non-Adherence in Patients with Dyslipidemia
Healthcare
adherence
dyslipidemia
statin
title Factors Associated with Medication Non-Adherence in Patients with Dyslipidemia
title_full Factors Associated with Medication Non-Adherence in Patients with Dyslipidemia
title_fullStr Factors Associated with Medication Non-Adherence in Patients with Dyslipidemia
title_full_unstemmed Factors Associated with Medication Non-Adherence in Patients with Dyslipidemia
title_short Factors Associated with Medication Non-Adherence in Patients with Dyslipidemia
title_sort factors associated with medication non adherence in patients with dyslipidemia
topic adherence
dyslipidemia
statin
url https://www.mdpi.com/2227-9032/9/7/813
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AT anansjarab factorsassociatedwithmedicationnonadherenceinpatientswithdyslipidemia
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AT linaabuzaytoun factorsassociatedwithmedicationnonadherenceinpatientswithdyslipidemia