Specific features of diagnosis of ankylosing spondylitis in the presence of uveitis in persons of different sex
<p align="LEFT">In patients with ankylosing spondylitis (AS), uveitis is its most common extraarticular manifestation (it occurs in 20–40% of cases).</p><strong><em><em></em></em></strong><p align="LEFT"><strong>Objectiv...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
IMA-PRESS LLC
2014-12-01
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| Series: | Современная ревматология |
| Subjects: | |
| Online Access: | http://mrj.ima-press.net/index.php/mrj/article/view/569 |
| Summary: | <p align="LEFT">In patients with ankylosing spondylitis (AS), uveitis is its most common extraarticular manifestation (it occurs in 20–40% of cases).</p><strong><em><em></em></em></strong><p align="LEFT"><strong>Objective</strong><span style="color: #231f20; font-family: NewtonC-Italic; font-size: xx-small;"><span style="color: #231f20; font-family: NewtonC-Italic; font-size: xx-small;"><span style="color: #231f20; font-family: NewtonC-Italic; font-size: xx-small;">: to study the specific features of diagnosis of AS in the presence of uveitis in persons of different sex.</span></span></span></p><strong><em><em></em></em></strong><p align="LEFT"><strong>Subjects and methods</strong><span style="color: #231f20; font-family: NewtonC-Italic; font-size: xx-small;"><span style="color: #231f20; font-family: NewtonC-Italic; font-size: xx-small;"><span style="color: #231f20; font-family: NewtonC-Italic; font-size: xx-small;">. The study included 94 patients with AS. The rate of uveitis, patient age at its first episode, in the clinical manifestations </span></span></span>of AS (inflammatory dorsalgia, arthritis, and enthesis), and in making a diagnosis, as well as disease activity were estimated in patients of different sex in the presence and absence of uveitis.</p><strong><em><em></em></em></strong><p align="LEFT"><strong>Results</strong><span style="color: #231f20; font-family: NewtonC-Italic; font-size: xx-small;"><span style="color: #231f20; font-family: NewtonC-Italic; font-size: xx-small;"><span style="color: #231f20; font-family: NewtonC-Italic; font-size: xx-small;">. Uveitis as an extraskeletal manifestation of AS was stablished to more common in women (40%) than in men (15.8%). In female </span></span></span>patients, the presence of uveitis is associated with early-onset AS as compared to those without uveitis. At the same time the diagnosis of AS was made in the women with uveitis 7 years later than in those without this condition. In one fifth of the patients, uveitis occurred before or concurrently with the appearance of the symptoms of locomotive lesion.</p><strong><em><em></em></em></strong><p><strong>Conclusion</strong><span style="color: #231f20; font-family: NewtonC-Italic; font-size: xx-small;"><span style="color: #231f20; font-family: NewtonC-Italic; font-size: xx-small;"><span style="color: #231f20; font-family: NewtonC-Italic; font-size: xx-small;">. Uveitis is more common in women with AS than in men and associated with the late detection of locomotive pathology. </span></span></span></p> |
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| ISSN: | 1996-7012 2310-158X |