PARK Genes Link Mitochondrial Dysfunction and Alpha-Synuclein Pathology in Sporadic Parkinson’s Disease

PARK Genes Link Mitochondrial Dysfunction and Alpha-Synuclein Pathology in Sporadic Parkinson’s Disease

Parkinson’s disease (PD) is an age-related neurodegenerative disorder affecting millions of people worldwide. The disease is characterized by the progressive loss of dopaminergic neurons and spread of Lewy pathology (α-synuclein aggregates) in the brain but the pathogenesis remains elusive. PD prese...

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Bibliographic Details
Main Authors:	Wen Li, YuHong Fu, Glenda M. Halliday, Carolyn M. Sue
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-07-01
Series:	Frontiers in Cell and Developmental Biology
Subjects:	Parkinson’s disease mitochondria mitophagy α-synuclein pathology PARK genes
Online Access:	https://www.frontiersin.org/articles/10.3389/fcell.2021.612476/full

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