Cost-effectiveness of spinal manipulation, exercise, and self-management for spinal pain using an individual participant data meta-analysis approach: a study protocol
Abstract Background Spinal pain is a common and disabling condition with considerable socioeconomic burden. Spine pain management in the United States has gathered increased scrutiny amidst concerns of overutilization of costly and potentially harmful interventions and diagnostic tests. Conservative...
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| Format: | Article |
| Language: | English |
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BMC
2018-11-01
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| Series: | Chiropractic & Manual Therapies |
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| Online Access: | http://link.springer.com/article/10.1186/s12998-018-0216-9 |
| _version_ | 1811206321305812992 |
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| author | Brent Leininger Gert Bronfort Roni Evans James Hodges Karen Kuntz John A. Nyman |
| author_facet | Brent Leininger Gert Bronfort Roni Evans James Hodges Karen Kuntz John A. Nyman |
| author_sort | Brent Leininger |
| collection | DOAJ |
| description | Abstract Background Spinal pain is a common and disabling condition with considerable socioeconomic burden. Spine pain management in the United States has gathered increased scrutiny amidst concerns of overutilization of costly and potentially harmful interventions and diagnostic tests. Conservative interventions such as spinal manipulation, exercise and self-management may provide value for the care of spinal pain, but little is known regarding the cost-effectiveness of these interventions in the U.S. Our primary objective for this project is to estimate the incremental cost-effectiveness of spinal manipulation, exercise therapy, and self-management for spinal pain using an individual patient data meta-analysis approach. Methods/design We will estimate the incremental cost-effectiveness of spinal manipulation, exercise therapy, and self-management using cost and clinical outcome data collected in eight randomized clinical trials performed in the U.S. Cost-effectiveness will be assessed from both societal and healthcare perspectives using QALYs, pain intensity, and disability as effectiveness measures. The eight randomized clinical trials used similar methods and included different combinations of spinal manipulation, exercise therapy, or self-management for spinal pain. They also collected similar clinical outcome, healthcare utilization, and work productivity data. A two-stage approach to individual patient data meta-analysis will be conducted. Discussion This project capitalizes on a unique opportunity to combine clinical and economic data collected in a several clinical trials that used similar methods. The findings will provide important information on the value of spinal manipulation, exercise therapy, and self-management for spinal pain management in the U.S. |
| first_indexed | 2024-04-12T03:45:56Z |
| format | Article |
| id | doaj.art-a548672196f040da9913d65164a5a28a |
| institution | Directory Open Access Journal |
| issn | 2045-709X |
| language | English |
| last_indexed | 2024-04-12T03:45:56Z |
| publishDate | 2018-11-01 |
| publisher | BMC |
| record_format | Article |
| series | Chiropractic & Manual Therapies |
| spelling | doaj.art-a548672196f040da9913d65164a5a28a2022-12-22T03:49:08ZengBMCChiropractic & Manual Therapies2045-709X2018-11-012611810.1186/s12998-018-0216-9Cost-effectiveness of spinal manipulation, exercise, and self-management for spinal pain using an individual participant data meta-analysis approach: a study protocolBrent Leininger0Gert Bronfort1Roni Evans2James Hodges3Karen Kuntz4John A. Nyman5Integrative Health & Wellbeing Research Program, Earl E. Bakken Center for Spirituality & Healing, University of MinnesotaIntegrative Health & Wellbeing Research Program, Earl E. Bakken Center for Spirituality & Healing, University of MinnesotaIntegrative Health & Wellbeing Research Program, Earl E. Bakken Center for Spirituality & Healing, University of MinnesotaDivision of Biostatistics, School of Public Health, University of MinnesotaDepartment of Health Policy and Management, University of MinnesotaDepartment of Health Policy and Management, University of MinnesotaAbstract Background Spinal pain is a common and disabling condition with considerable socioeconomic burden. Spine pain management in the United States has gathered increased scrutiny amidst concerns of overutilization of costly and potentially harmful interventions and diagnostic tests. Conservative interventions such as spinal manipulation, exercise and self-management may provide value for the care of spinal pain, but little is known regarding the cost-effectiveness of these interventions in the U.S. Our primary objective for this project is to estimate the incremental cost-effectiveness of spinal manipulation, exercise therapy, and self-management for spinal pain using an individual patient data meta-analysis approach. Methods/design We will estimate the incremental cost-effectiveness of spinal manipulation, exercise therapy, and self-management using cost and clinical outcome data collected in eight randomized clinical trials performed in the U.S. Cost-effectiveness will be assessed from both societal and healthcare perspectives using QALYs, pain intensity, and disability as effectiveness measures. The eight randomized clinical trials used similar methods and included different combinations of spinal manipulation, exercise therapy, or self-management for spinal pain. They also collected similar clinical outcome, healthcare utilization, and work productivity data. A two-stage approach to individual patient data meta-analysis will be conducted. Discussion This project capitalizes on a unique opportunity to combine clinical and economic data collected in a several clinical trials that used similar methods. The findings will provide important information on the value of spinal manipulation, exercise therapy, and self-management for spinal pain management in the U.S.http://link.springer.com/article/10.1186/s12998-018-0216-9Cost-effectivenessBack painNeck painExerciseSpinal manipulationSelf-care |
| spellingShingle | Brent Leininger Gert Bronfort Roni Evans James Hodges Karen Kuntz John A. Nyman Cost-effectiveness of spinal manipulation, exercise, and self-management for spinal pain using an individual participant data meta-analysis approach: a study protocol Chiropractic & Manual Therapies Cost-effectiveness Back pain Neck pain Exercise Spinal manipulation Self-care |
| title | Cost-effectiveness of spinal manipulation, exercise, and self-management for spinal pain using an individual participant data meta-analysis approach: a study protocol |
| title_full | Cost-effectiveness of spinal manipulation, exercise, and self-management for spinal pain using an individual participant data meta-analysis approach: a study protocol |
| title_fullStr | Cost-effectiveness of spinal manipulation, exercise, and self-management for spinal pain using an individual participant data meta-analysis approach: a study protocol |
| title_full_unstemmed | Cost-effectiveness of spinal manipulation, exercise, and self-management for spinal pain using an individual participant data meta-analysis approach: a study protocol |
| title_short | Cost-effectiveness of spinal manipulation, exercise, and self-management for spinal pain using an individual participant data meta-analysis approach: a study protocol |
| title_sort | cost effectiveness of spinal manipulation exercise and self management for spinal pain using an individual participant data meta analysis approach a study protocol |
| topic | Cost-effectiveness Back pain Neck pain Exercise Spinal manipulation Self-care |
| url | http://link.springer.com/article/10.1186/s12998-018-0216-9 |
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