The Coexistence of extended spectrum β lactamases and AmpC production among uropathogenic isolates of Escherichia coli and its antibiogram pattern
Emergence of drug resistance in Escherichia coli due to various mechanisms makes the treatment choices very limited. The objective of this research was to investigate extended-spectrum beta-lactamases (ESBLs) and AmpC lactamases in E. coli isolates from urinary tract infections (UTIs) and to...
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| Format: | Article |
| Language: | English |
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Koya University
2022-06-01
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| Series: | ARO-The Scientific Journal of Koya University |
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| Online Access: | https://aro.koyauniversity.org/index.php/aro/article/view/898 |
| _version_ | 1797720998345179136 |
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| author | Aryan R. Ganjo |
| author_facet | Aryan R. Ganjo |
| author_sort | Aryan R. Ganjo |
| collection | DOAJ |
| description |
Emergence of drug resistance in Escherichia coli due to various mechanisms makes the treatment choices very limited. The objective of this research was to investigate extended-spectrum beta-lactamases (ESBLs) and AmpC lactamases in E. coli isolates from urinary tract infections (UTIs) and to assess their antibacterial susceptibility patterns in a health-care context. A total of 70 E. coli isolates from clinically assumed cases of UTI patients during the 9 months period. The isolates with bacteriuria (105 CFU/ml) were identified. ESBL and AmpC were detected phenotypically. Out of the 70 isolates of uropathogenic E. coli, ESBL production was detected in 34 (48.6%) isolates and AmpC producer in 27 (38.6%) of isolates in which 14 (20%) of them showed coexistence phenotype of both ESBLs and AmpC and 23 (32.9%) E. coli isolates were both ESBL and AmpC non-producer. The findings donated information regarding drug resistance. The level of resistance recorded in ESBL- and AmpC-producing uropathogenic E. coli of this study was raising; therefore, it is crucial to have a strict infection control measures and routine monitoring of ESBL- and AmpC-producing bacteria in clinical laboratory.
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| first_indexed | 2024-03-12T09:28:32Z |
| format | Article |
| id | doaj.art-a548f4f7ed3f4de0baad80efbe7e2c0f |
| institution | Directory Open Access Journal |
| issn | 2410-9355 2307-549X |
| language | English |
| last_indexed | 2024-03-12T09:28:32Z |
| publishDate | 2022-06-01 |
| publisher | Koya University |
| record_format | Article |
| series | ARO-The Scientific Journal of Koya University |
| spelling | doaj.art-a548f4f7ed3f4de0baad80efbe7e2c0f2023-09-02T14:03:52ZengKoya UniversityARO-The Scientific Journal of Koya University2410-93552307-549X2022-06-0110110.14500/aro.10898The Coexistence of extended spectrum β lactamases and AmpC production among uropathogenic isolates of Escherichia coli and its antibiogram patternAryan R. Ganjo0Department of Pharmacognosy, College of Pharmacy, Hawler Medical University Erbil, Kurdistan Region – F.R. Iraq Emergence of drug resistance in Escherichia coli due to various mechanisms makes the treatment choices very limited. The objective of this research was to investigate extended-spectrum beta-lactamases (ESBLs) and AmpC lactamases in E. coli isolates from urinary tract infections (UTIs) and to assess their antibacterial susceptibility patterns in a health-care context. A total of 70 E. coli isolates from clinically assumed cases of UTI patients during the 9 months period. The isolates with bacteriuria (105 CFU/ml) were identified. ESBL and AmpC were detected phenotypically. Out of the 70 isolates of uropathogenic E. coli, ESBL production was detected in 34 (48.6%) isolates and AmpC producer in 27 (38.6%) of isolates in which 14 (20%) of them showed coexistence phenotype of both ESBLs and AmpC and 23 (32.9%) E. coli isolates were both ESBL and AmpC non-producer. The findings donated information regarding drug resistance. The level of resistance recorded in ESBL- and AmpC-producing uropathogenic E. coli of this study was raising; therefore, it is crucial to have a strict infection control measures and routine monitoring of ESBL- and AmpC-producing bacteria in clinical laboratory. https://aro.koyauniversity.org/index.php/aro/article/view/898AmpC, extended spectrum beta-lactamse (ESBL), Escherichia coli, urinary tract infections |
| spellingShingle | Aryan R. Ganjo The Coexistence of extended spectrum β lactamases and AmpC production among uropathogenic isolates of Escherichia coli and its antibiogram pattern ARO-The Scientific Journal of Koya University AmpC, extended spectrum beta-lactamse (ESBL), Escherichia coli, urinary tract infections |
| title | The Coexistence of extended spectrum β lactamases and AmpC production among uropathogenic isolates of Escherichia coli and its antibiogram pattern |
| title_full | The Coexistence of extended spectrum β lactamases and AmpC production among uropathogenic isolates of Escherichia coli and its antibiogram pattern |
| title_fullStr | The Coexistence of extended spectrum β lactamases and AmpC production among uropathogenic isolates of Escherichia coli and its antibiogram pattern |
| title_full_unstemmed | The Coexistence of extended spectrum β lactamases and AmpC production among uropathogenic isolates of Escherichia coli and its antibiogram pattern |
| title_short | The Coexistence of extended spectrum β lactamases and AmpC production among uropathogenic isolates of Escherichia coli and its antibiogram pattern |
| title_sort | coexistence of extended spectrum β lactamases and ampc production among uropathogenic isolates of escherichia coli and its antibiogram pattern |
| topic | AmpC, extended spectrum beta-lactamse (ESBL), Escherichia coli, urinary tract infections |
| url | https://aro.koyauniversity.org/index.php/aro/article/view/898 |
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