The association of serum uric acid/albumin ratio with the development of coronary collateral circulation in patients with chronic total occluded coronary arteries
Introduction: Coronary collateral circulation (CCC) develops in chronic total occluded (CTO) vessels and protects the myocardium against ischemia in addition to the improvement of cardiac functions. Poor CCC is related to adverse cardiac events as well as poor prognosis. Serum uric acid/albumin rati...
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| Format: | Article |
| Language: | English |
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Tabriz University of Medical Sciences
2023-03-01
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| Series: | Journal of Cardiovascular and Thoracic Research |
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| Online Access: | https://jcvtr.tbzmed.ac.ir/PDF/jcvtr-15-14.pdf |
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| author | Faysal Şaylık Tufan Çınar Remzi Sarıkaya Tayyar Akbulut Murat Selçuk Emrah Özbek Halil İbrahim Tanboğa |
| author_facet | Faysal Şaylık Tufan Çınar Remzi Sarıkaya Tayyar Akbulut Murat Selçuk Emrah Özbek Halil İbrahim Tanboğa |
| author_sort | Faysal Şaylık |
| collection | DOAJ |
| description | Introduction: Coronary collateral circulation (CCC) develops in chronic total occluded (CTO) vessels and protects the myocardium against ischemia in addition to the improvement of cardiac functions. Poor CCC is related to adverse cardiac events as well as poor prognosis. Serum uric acid/albumin ratio (UAR) has emerged as a novel marker associated with poor cardiovascular outcomes. We aimed to investigate whether there was an association between UAR and poor CCC in CTO patients. Methods: This study was comprised of 212 patients with CTO (92 with poor CCC and 120 with good CCC). All patients were graded based on Rentrop scores to poor CCC (Rentrop scores 0 and 1) and good CCC (Rentrop scores 2 and 3). Results: Poor CCC patients had higher frequencies of diabetes mellitus, triglyceride levels, Syntax and Gensini scores, uric acid, and UAR and lower lymphocyte, high-density lipoprotein cholesterol, and ejection fraction when compared to good CCC patients. UAR was an independent predictor of poor CCC in CTO patients. Furthermore, UAR had a better discriminative ability for patients with poor CCC from good CCC compared to serum uric acid and albumin. Conclusion: Based on the results of the study, the UAR could be used to detect poor CCC in CTO patients. |
| first_indexed | 2024-03-13T05:53:07Z |
| format | Article |
| id | doaj.art-a55351f59bfc4e7aa15a3e414728c664 |
| institution | Directory Open Access Journal |
| issn | 2008-5117 2008-6830 |
| language | English |
| last_indexed | 2024-03-13T05:53:07Z |
| publishDate | 2023-03-01 |
| publisher | Tabriz University of Medical Sciences |
| record_format | Article |
| series | Journal of Cardiovascular and Thoracic Research |
| spelling | doaj.art-a55351f59bfc4e7aa15a3e414728c6642023-06-13T08:19:05ZengTabriz University of Medical SciencesJournal of Cardiovascular and Thoracic Research2008-51172008-68302023-03-01151142110.34172/jcvtr.2023.31627jcvtr-31627The association of serum uric acid/albumin ratio with the development of coronary collateral circulation in patients with chronic total occluded coronary arteriesFaysal Şaylık0Tufan Çınar1Remzi Sarıkaya2Tayyar Akbulut3Murat Selçuk4Emrah Özbek5Halil İbrahim Tanboğa6Department of Cardiology, Van Education and Research Hospital, Van, TurkeyDepartment of Cardiology, Sultan Abdulhamid Han Education and Research Hospital, Istanbul, TurkeyDepartment of Cardiology, Van Education and Research Hospital, Van, TurkeyDepartment of Cardiology, Van Education and Research Hospital, Van, TurkeyDepartment of Cardiology, Sultan Abdulhamid Han Education and Research Hospital, Istanbul, TurkeyDepartment of Cardiology, Van Education and Research Hospital, Van, TurkeyDepartment of Cardiology and Biostatistics, Istanbul Nisantasi University, Istanbul, TurkeyIntroduction: Coronary collateral circulation (CCC) develops in chronic total occluded (CTO) vessels and protects the myocardium against ischemia in addition to the improvement of cardiac functions. Poor CCC is related to adverse cardiac events as well as poor prognosis. Serum uric acid/albumin ratio (UAR) has emerged as a novel marker associated with poor cardiovascular outcomes. We aimed to investigate whether there was an association between UAR and poor CCC in CTO patients. Methods: This study was comprised of 212 patients with CTO (92 with poor CCC and 120 with good CCC). All patients were graded based on Rentrop scores to poor CCC (Rentrop scores 0 and 1) and good CCC (Rentrop scores 2 and 3). Results: Poor CCC patients had higher frequencies of diabetes mellitus, triglyceride levels, Syntax and Gensini scores, uric acid, and UAR and lower lymphocyte, high-density lipoprotein cholesterol, and ejection fraction when compared to good CCC patients. UAR was an independent predictor of poor CCC in CTO patients. Furthermore, UAR had a better discriminative ability for patients with poor CCC from good CCC compared to serum uric acid and albumin. Conclusion: Based on the results of the study, the UAR could be used to detect poor CCC in CTO patients.https://jcvtr.tbzmed.ac.ir/PDF/jcvtr-15-14.pdfrentrop scorechronic total occlusioncoronary collateral circulationuric acid/ albumin ratio |
| spellingShingle | Faysal Şaylık Tufan Çınar Remzi Sarıkaya Tayyar Akbulut Murat Selçuk Emrah Özbek Halil İbrahim Tanboğa The association of serum uric acid/albumin ratio with the development of coronary collateral circulation in patients with chronic total occluded coronary arteries Journal of Cardiovascular and Thoracic Research rentrop score chronic total occlusion coronary collateral circulation uric acid/ albumin ratio |
| title | The association of serum uric acid/albumin ratio with the development of coronary collateral circulation in patients with chronic total occluded coronary arteries |
| title_full | The association of serum uric acid/albumin ratio with the development of coronary collateral circulation in patients with chronic total occluded coronary arteries |
| title_fullStr | The association of serum uric acid/albumin ratio with the development of coronary collateral circulation in patients with chronic total occluded coronary arteries |
| title_full_unstemmed | The association of serum uric acid/albumin ratio with the development of coronary collateral circulation in patients with chronic total occluded coronary arteries |
| title_short | The association of serum uric acid/albumin ratio with the development of coronary collateral circulation in patients with chronic total occluded coronary arteries |
| title_sort | association of serum uric acid albumin ratio with the development of coronary collateral circulation in patients with chronic total occluded coronary arteries |
| topic | rentrop score chronic total occlusion coronary collateral circulation uric acid/ albumin ratio |
| url | https://jcvtr.tbzmed.ac.ir/PDF/jcvtr-15-14.pdf |
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