Clinical and Histopathological Evaluation of Healing After Excision of Leukoplakia with Diode Laser

Aim: Oral Leukoplakia is considered commonest precancerous white lesion affecting oral mucosa. There are several medicinal and surgical options available to treat the lesion. Scalpel removal of the lesion leads to scar formation and pain along with bleeding at the time of surgery. Removal with Laser...

Full description

Bibliographic Details
Main Authors: Kruti A Shah, Hemal R Brahmkshatriya, Rushit J Patel, Mansi H Brahmkshatriya
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2014-01-01
Series:Advances in Human Biology
Subjects:
Online Access:http://www.aihbonline.com/article.asp?issn=2321-8568;year=2014;volume=4;issue=2;spage=45;epage=49;aulast=Shah;type=0
_version_ 1818302497454817280
author Kruti A Shah
Hemal R Brahmkshatriya
Rushit J Patel
Mansi H Brahmkshatriya
author_facet Kruti A Shah
Hemal R Brahmkshatriya
Rushit J Patel
Mansi H Brahmkshatriya
author_sort Kruti A Shah
collection DOAJ
description Aim: Oral Leukoplakia is considered commonest precancerous white lesion affecting oral mucosa. There are several medicinal and surgical options available to treat the lesion. Scalpel removal of the lesion leads to scar formation and pain along with bleeding at the time of surgery. Removal with Laser is another option for managing leukoplakia. There are very few studies present with removal of leukoplakia using Diode Laser. This study was undertaken to clinically and histopathologically evaluate the efficacy of Diode Laser in leukoplakia. Materials and Method: Six patients, 5 male (84%) and 1 female (16%) with leukoplakia were treated with Diode laser (980nm) at 3 - 4 watts. Patients on steroid therapy or immune-suppressants and suffering from any other chronic debilitating diseases were excluded from the study. Wilcoxon Signed Ranks Test was applied for assessing the p-Value for statistical analysis. Result: After one month, the patients were examined for normal clinical healing of the site. For more confirmation, re-biopsy was done and result showed normal tissue healing except in one patient (16%). Only one patient (16%) developed pain, swelling, fibrosis and recurrence. Conclusion: It was concluded that laser provides good coagulation, healing, reduces surgical time and prevents high-grade infection.
first_indexed 2024-12-13T05:39:51Z
format Article
id doaj.art-a5553855032a442483c7de88c2543d25
institution Directory Open Access Journal
issn 2321-8568
2348-4691
language English
last_indexed 2024-12-13T05:39:51Z
publishDate 2014-01-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Advances in Human Biology
spelling doaj.art-a5553855032a442483c7de88c2543d252022-12-21T23:57:49ZengWolters Kluwer Medknow PublicationsAdvances in Human Biology2321-85682348-46912014-01-01424549Clinical and Histopathological Evaluation of Healing After Excision of Leukoplakia with Diode LaserKruti A ShahHemal R BrahmkshatriyaRushit J PatelMansi H BrahmkshatriyaAim: Oral Leukoplakia is considered commonest precancerous white lesion affecting oral mucosa. There are several medicinal and surgical options available to treat the lesion. Scalpel removal of the lesion leads to scar formation and pain along with bleeding at the time of surgery. Removal with Laser is another option for managing leukoplakia. There are very few studies present with removal of leukoplakia using Diode Laser. This study was undertaken to clinically and histopathologically evaluate the efficacy of Diode Laser in leukoplakia. Materials and Method: Six patients, 5 male (84%) and 1 female (16%) with leukoplakia were treated with Diode laser (980nm) at 3 - 4 watts. Patients on steroid therapy or immune-suppressants and suffering from any other chronic debilitating diseases were excluded from the study. Wilcoxon Signed Ranks Test was applied for assessing the p-Value for statistical analysis. Result: After one month, the patients were examined for normal clinical healing of the site. For more confirmation, re-biopsy was done and result showed normal tissue healing except in one patient (16%). Only one patient (16%) developed pain, swelling, fibrosis and recurrence. Conclusion: It was concluded that laser provides good coagulation, healing, reduces surgical time and prevents high-grade infection.http://www.aihbonline.com/article.asp?issn=2321-8568;year=2014;volume=4;issue=2;spage=45;epage=49;aulast=Shah;type=0Diode LaserWound healingLeukoplakiaHistology.
spellingShingle Kruti A Shah
Hemal R Brahmkshatriya
Rushit J Patel
Mansi H Brahmkshatriya
Clinical and Histopathological Evaluation of Healing After Excision of Leukoplakia with Diode Laser
Advances in Human Biology
Diode Laser
Wound healing
Leukoplakia
Histology.
title Clinical and Histopathological Evaluation of Healing After Excision of Leukoplakia with Diode Laser
title_full Clinical and Histopathological Evaluation of Healing After Excision of Leukoplakia with Diode Laser
title_fullStr Clinical and Histopathological Evaluation of Healing After Excision of Leukoplakia with Diode Laser
title_full_unstemmed Clinical and Histopathological Evaluation of Healing After Excision of Leukoplakia with Diode Laser
title_short Clinical and Histopathological Evaluation of Healing After Excision of Leukoplakia with Diode Laser
title_sort clinical and histopathological evaluation of healing after excision of leukoplakia with diode laser
topic Diode Laser
Wound healing
Leukoplakia
Histology.
url http://www.aihbonline.com/article.asp?issn=2321-8568;year=2014;volume=4;issue=2;spage=45;epage=49;aulast=Shah;type=0
work_keys_str_mv AT krutiashah clinicalandhistopathologicalevaluationofhealingafterexcisionofleukoplakiawithdiodelaser
AT hemalrbrahmkshatriya clinicalandhistopathologicalevaluationofhealingafterexcisionofleukoplakiawithdiodelaser
AT rushitjpatel clinicalandhistopathologicalevaluationofhealingafterexcisionofleukoplakiawithdiodelaser
AT mansihbrahmkshatriya clinicalandhistopathologicalevaluationofhealingafterexcisionofleukoplakiawithdiodelaser