A case-control study to identify risk factors for adult-onset idiopathic megaoesophagus in Australian dogs, 2017–2018
Abstract Background Epidemiological investigations were carried out following detection of an outbreak of megaoesophagus in Victorian Police working dogs in early 2018 and an increase in the number of canine megaoesophagus cases reported by companion animal veterinarians in Eastern Australia startin...
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| Format: | Article |
| Language: | English |
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BMC
2020-05-01
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| Series: | BMC Veterinary Research |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12917-020-02376-6 |
| _version_ | 1818152498561548288 |
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| author | M. Renwick M. A. Stevenson A. Wiethoelter C. Mansfield |
| author_facet | M. Renwick M. A. Stevenson A. Wiethoelter C. Mansfield |
| author_sort | M. Renwick |
| collection | DOAJ |
| description | Abstract Background Epidemiological investigations were carried out following detection of an outbreak of megaoesophagus in Victorian Police working dogs in early 2018 and an increase in the number of canine megaoesophagus cases reported by companion animal veterinarians in Eastern Australia starting in late 2017. VetCompass Australia data were used to quantify the incidence of canine megaoesophagus for the period January 2012 to February 2018 and a matched case-control study carried out to identify individual animal risk factors for canine megaoesophagus in 2017–2018. Results There was a 7-fold increase in the incidence rate of canine megaoesophagus from 2014 (0.11 [95% CI 0.02 to 0.58] cases per 100,000 dogs per day) to 2018 (0.82 [95% CI 0.19 to 4.2] cases per 100,000 dogs per day). Since 2013, the incidence of megaoesophagus in Australia has shown a seasonal pattern, with greater numbers of cases diagnosed during the warmer months of the year. In the case-control study, use of Mars Petcare Advance Dermocare as a source of food was 325 (95% CI 64 to 1644) times greater for cases, compared with controls. Conclusions Our analyses provide evidence that the feeding of Advance Dermocare was responsible for the majority of cases in the outbreak of megaoesophagus in Eastern Australia in 2017–2018. The increase in the incidence rate of megaoesophagus in Australia since 2014–2015 warrants further investigation. |
| first_indexed | 2024-12-11T13:55:41Z |
| format | Article |
| id | doaj.art-a555cf4e150d42ca9867c12a88e8cc3d |
| institution | Directory Open Access Journal |
| issn | 1746-6148 |
| language | English |
| last_indexed | 2024-12-11T13:55:41Z |
| publishDate | 2020-05-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Veterinary Research |
| spelling | doaj.art-a555cf4e150d42ca9867c12a88e8cc3d2022-12-22T01:04:05ZengBMCBMC Veterinary Research1746-61482020-05-011611910.1186/s12917-020-02376-6A case-control study to identify risk factors for adult-onset idiopathic megaoesophagus in Australian dogs, 2017–2018M. Renwick0M. A. Stevenson1A. Wiethoelter2C. Mansfield3Faculty of Veterinary and Agricultural Sciences, The University of MelbourneFaculty of Veterinary and Agricultural Sciences, The University of MelbourneFaculty of Veterinary and Agricultural Sciences, The University of MelbourneFaculty of Veterinary and Agricultural Sciences, The University of MelbourneAbstract Background Epidemiological investigations were carried out following detection of an outbreak of megaoesophagus in Victorian Police working dogs in early 2018 and an increase in the number of canine megaoesophagus cases reported by companion animal veterinarians in Eastern Australia starting in late 2017. VetCompass Australia data were used to quantify the incidence of canine megaoesophagus for the period January 2012 to February 2018 and a matched case-control study carried out to identify individual animal risk factors for canine megaoesophagus in 2017–2018. Results There was a 7-fold increase in the incidence rate of canine megaoesophagus from 2014 (0.11 [95% CI 0.02 to 0.58] cases per 100,000 dogs per day) to 2018 (0.82 [95% CI 0.19 to 4.2] cases per 100,000 dogs per day). Since 2013, the incidence of megaoesophagus in Australia has shown a seasonal pattern, with greater numbers of cases diagnosed during the warmer months of the year. In the case-control study, use of Mars Petcare Advance Dermocare as a source of food was 325 (95% CI 64 to 1644) times greater for cases, compared with controls. Conclusions Our analyses provide evidence that the feeding of Advance Dermocare was responsible for the majority of cases in the outbreak of megaoesophagus in Eastern Australia in 2017–2018. The increase in the incidence rate of megaoesophagus in Australia since 2014–2015 warrants further investigation.http://link.springer.com/article/10.1186/s12917-020-02376-6Canine megaoesophagusEpidemiologyCase-control studyOutbreak investigation |
| spellingShingle | M. Renwick M. A. Stevenson A. Wiethoelter C. Mansfield A case-control study to identify risk factors for adult-onset idiopathic megaoesophagus in Australian dogs, 2017–2018 BMC Veterinary Research Canine megaoesophagus Epidemiology Case-control study Outbreak investigation |
| title | A case-control study to identify risk factors for adult-onset idiopathic megaoesophagus in Australian dogs, 2017–2018 |
| title_full | A case-control study to identify risk factors for adult-onset idiopathic megaoesophagus in Australian dogs, 2017–2018 |
| title_fullStr | A case-control study to identify risk factors for adult-onset idiopathic megaoesophagus in Australian dogs, 2017–2018 |
| title_full_unstemmed | A case-control study to identify risk factors for adult-onset idiopathic megaoesophagus in Australian dogs, 2017–2018 |
| title_short | A case-control study to identify risk factors for adult-onset idiopathic megaoesophagus in Australian dogs, 2017–2018 |
| title_sort | case control study to identify risk factors for adult onset idiopathic megaoesophagus in australian dogs 2017 2018 |
| topic | Canine megaoesophagus Epidemiology Case-control study Outbreak investigation |
| url | http://link.springer.com/article/10.1186/s12917-020-02376-6 |
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