Chemokine Receptor 5 Antagonism Causes Reduction in Joint Inflammation in a Collagen-Induced Arthritis Mouse Model

Chemokine Receptor 5 Antagonism Causes Reduction in Joint Inflammation in a Collagen-Induced Arthritis Mouse Model

Rheumatoid arthritis (RA) is a chronic inflammatory disease mainly affecting the synovial joints. A highly potent antagonist of C-C chemokine receptor 5 (CCR5), maraviroc (MVC), plays an essential role in treating several infectious diseases but has not yet been evaluated for its potential effects o...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Mushtaq A. Ansari, Ahmed Nadeem, Saleh A. Bakheet, Sabry M. Attia, Mudassar Shahid, Faris S. Alyousef, Mohammed A. Alswailem, Mohammed Alqinyah, Sheikh F. Ahmad
Format: Artikel
Sprache:English
Veröffentlicht: MDPI AG 2021-03-01
Schriftenreihe:Molecules
Schlagworte:
maraviroc
CCR5 antagonist
inflammation
collagen-induced arthritis
CD8 cells
Online Zugang:https://www.mdpi.com/1420-3049/26/7/1839

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https://www.mdpi.com/1420-3049/26/7/1839

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