Inflammatory Markers as Predictors for Prolonged Duration of Hospitalization in Maxillofacial Infections
Despite the progress made in diagnosing and treating maxillofacial infections, the course of infection can be unpredictable, leading to severe complications, prolonged hospitalization, and substantial financial costs to health care services. It is important to determine whether various serum inflamm...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-01-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/12/3/871 |
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| author | Horatiu Urechescu Eleonora Gheran-Vida Cristiana Cuzic Oana Ancusa Sorin Ursoniu Marius Pricop |
| author_facet | Horatiu Urechescu Eleonora Gheran-Vida Cristiana Cuzic Oana Ancusa Sorin Ursoniu Marius Pricop |
| author_sort | Horatiu Urechescu |
| collection | DOAJ |
| description | Despite the progress made in diagnosing and treating maxillofacial infections, the course of infection can be unpredictable, leading to severe complications, prolonged hospitalization, and substantial financial costs to health care services. It is important to determine whether various serum inflammatory marker levels on admission may predict a prolonged hospital stay in these patients. To analyze the role of CRP, white blood cell count (WBC), and neutrophil-to-lymphocyte ratio (NLR) in predicting the prolonged duration of hospitalization in maxillofacial infections, we performed a retrospective study by collecting paper records data from 108 patients who met our inclusion criteria. The patients were divided into two groups according to the duration of hospitalization (group A < 5 days and group B ≥ 5 days). The predictor variables were CRP, WBC, and NLR, and the outcome variable was the duration of hospitalization. This study confirmed a positive linear correlation (<i>p</i> < 0.001) between the predictors and the outcome variable. The optimal cut-off values for WBC are 11,030 white blood cells/μL and 63 mg/L for CRP. Levels that exceed these optimal values predict a duration of hospitalization of over (≥) 5 days. Serum WBC and CRP on admission may predict the duration of hospitalization in patients with MFI. |
| first_indexed | 2024-03-11T09:39:08Z |
| format | Article |
| id | doaj.art-a556662e65cf4f7ba63b57281492cbde |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-11T09:39:08Z |
| publishDate | 2023-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-a556662e65cf4f7ba63b57281492cbde2023-11-16T17:08:22ZengMDPI AGJournal of Clinical Medicine2077-03832023-01-0112387110.3390/jcm12030871Inflammatory Markers as Predictors for Prolonged Duration of Hospitalization in Maxillofacial InfectionsHoratiu Urechescu0Eleonora Gheran-Vida1Cristiana Cuzic2Oana Ancusa3Sorin Ursoniu4Marius Pricop5Discipline of Oral and Maxillo-Facial Surgery, Faculty of Dental Medicine, “Victor Babes” University of Medicine and Pharmacy Timisoara, Eftimie Murgu Square 2, 300041 Timisoara, RomaniaTimisoara Emergency Clinical Municipal Hospital, Hector 1 Street, 300041 Timisoara, RomaniaDepartment of Prosthodontics, Faculty of Dental Medicine, “Victor Babes” University of Medicine and Pharmacy, Eftimie Murgu Square 2, 300041 Timisoara, RomaniaDepartment V, Discipline of Medical Semiology I, Faculty of General Medicine, “Victor Babes” University of Medicine and Pharmacy Timisoara, Eftimie Murgu Square 2, 300041 Timisoara, RomaniaDepartment of Functional Sciences, Center for Translational Research and Systems Medicine, “Victor Babes” University of Medicine and Pharmacy, Eftimie Murgu Square 2, 300041 Timisoara, RomaniaDiscipline of Oral and Maxillo-Facial Surgery, Faculty of Dental Medicine, “Victor Babes” University of Medicine and Pharmacy Timisoara, Eftimie Murgu Square 2, 300041 Timisoara, RomaniaDespite the progress made in diagnosing and treating maxillofacial infections, the course of infection can be unpredictable, leading to severe complications, prolonged hospitalization, and substantial financial costs to health care services. It is important to determine whether various serum inflammatory marker levels on admission may predict a prolonged hospital stay in these patients. To analyze the role of CRP, white blood cell count (WBC), and neutrophil-to-lymphocyte ratio (NLR) in predicting the prolonged duration of hospitalization in maxillofacial infections, we performed a retrospective study by collecting paper records data from 108 patients who met our inclusion criteria. The patients were divided into two groups according to the duration of hospitalization (group A < 5 days and group B ≥ 5 days). The predictor variables were CRP, WBC, and NLR, and the outcome variable was the duration of hospitalization. This study confirmed a positive linear correlation (<i>p</i> < 0.001) between the predictors and the outcome variable. The optimal cut-off values for WBC are 11,030 white blood cells/μL and 63 mg/L for CRP. Levels that exceed these optimal values predict a duration of hospitalization of over (≥) 5 days. Serum WBC and CRP on admission may predict the duration of hospitalization in patients with MFI.https://www.mdpi.com/2077-0383/12/3/871health care servicesC-reactive protein (CRP)hemogram indexesmaxillofacial infection (MFI)white blood cell count (WBC) |
| spellingShingle | Horatiu Urechescu Eleonora Gheran-Vida Cristiana Cuzic Oana Ancusa Sorin Ursoniu Marius Pricop Inflammatory Markers as Predictors for Prolonged Duration of Hospitalization in Maxillofacial Infections Journal of Clinical Medicine health care services C-reactive protein (CRP) hemogram indexes maxillofacial infection (MFI) white blood cell count (WBC) |
| title | Inflammatory Markers as Predictors for Prolonged Duration of Hospitalization in Maxillofacial Infections |
| title_full | Inflammatory Markers as Predictors for Prolonged Duration of Hospitalization in Maxillofacial Infections |
| title_fullStr | Inflammatory Markers as Predictors for Prolonged Duration of Hospitalization in Maxillofacial Infections |
| title_full_unstemmed | Inflammatory Markers as Predictors for Prolonged Duration of Hospitalization in Maxillofacial Infections |
| title_short | Inflammatory Markers as Predictors for Prolonged Duration of Hospitalization in Maxillofacial Infections |
| title_sort | inflammatory markers as predictors for prolonged duration of hospitalization in maxillofacial infections |
| topic | health care services C-reactive protein (CRP) hemogram indexes maxillofacial infection (MFI) white blood cell count (WBC) |
| url | https://www.mdpi.com/2077-0383/12/3/871 |
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