Bushen-Yizhi formula ameliorates mitochondrial dysfunction and oxidative stress via AMPK/Sirt1 signaling pathway in D-gal-induced aging rats

Bushen-Yizhi formula ameliorates mitochondrial dysfunction and oxidative stress via AMPK/Sirt1 signaling pathway in D-gal-induced aging rats

Abstract Background As a major risk factor for neurodegenerative diseases, aging has become a heavy health care burden worldwide. Age-related decline in mitochondrial function and oxidative stress is strongly associated with neurodegeneration. The previous study demonstrated that Bushen-Yizhi formul...

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Bibliographic Details
Main Authors: Yanfang Liao, Yiyi Lai, Huilin Xu, Li Gao, Xiaomei Fu, Xue Wang, Qi Wang, Jiangang Shen, Jiansong Fang, Shuhuan Fang
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Chinese Medicine
Subjects:
Bushen-Yizhi formula
D-galactose-induced-aging rats
Metabolomics
Mitochondrial dysfunction
Oxidative stress
Inflammation
Online Access:https://doi.org/10.1186/s13020-023-00755-3

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