Effects of dietary lysozyme supplementation on growth performance, nutrient digestibility, intestinal microbiota, and blood profiles of weanling pigs challenged with Escherichia coli
The aim of this was evaluate the efficacy of lysozyme on growth performance, nutrient digestibility, excreta microflora population, and blood profiles of weanling pigs under Escherichia coli (E. coli) challenge. A total of 30 piglets weaned...
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| Format: | Article |
| Language: | English |
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Korean Society of Animal Sciences and Technology
2021-05-01
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| Series: | Journal of Animal Science and Technology |
| Subjects: | |
| Online Access: | http://www.ejast.org/archive/view_article?pid=jast-63-3-501 |
| _version_ | 1818644715512266752 |
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| author | Jae Hong Park Shanmugam Sureshkumar In Ho Kim |
| author_facet | Jae Hong Park Shanmugam Sureshkumar In Ho Kim |
| author_sort | Jae Hong Park |
| collection | DOAJ |
| description | The aim of this was evaluate the efficacy of lysozyme on growth performance,
nutrient digestibility, excreta microflora population, and blood profiles of
weanling pigs under Escherichia coli (E. coli)
challenge. A total of 30 piglets weaned at 25 days, 7.46 kg body weight, were
assigned to three dietary treatments, composed of five replications, two piglets
per replication, for 7 days. The dietary treatment groups were negative control
(NC; without antibiotics and lysozyme), positive control (PC; NC + antibiotics),
lysozyme (NC + 0.1% lysozyme). All piglets were challenged orally with 6 ml
suspension, containing E. coli K88 (2 × 109
CFU/mL). Dietary supplementation with lysozyme and PC resulted in no significant
differences in average daily gain and gain to feed efficiency. Weanling pigs fed
with E. coli challenge with lysozyme and PC treatments had
significantly enhanced nutrient retentions of dry matter and energy
(p < 0.05); however, there was a tendency to
increase nitrogen digestibility. Furthermore, dietary inclusion of lysozyme and
antibiotics treatment groups had a beneficial effect on excreta, ileal, and
cecal of the fecal microbial population as decreased E. coli
(p < 0.05) counts, without effects on
lactobacillus counts. A significant effect were observed on
a white blood cells, epinephrine and cortisol concentrations were reduced in
piglets fed diets containing E. coli challenge with lysozyme
and antibiotics supplementation comparison with the NC group. Therefore, the
present data indicate that lysozyme in diet could ameliorate the experimental
stress response induced by E. coli in piglets by decreasing
intestinal E. coli, white blood cells and stress hormones and
improving nutrient digestibility. |
| first_indexed | 2024-12-17T00:19:15Z |
| format | Article |
| id | doaj.art-a5589233a1ba4e29b7e85ce7c8bc0b3b |
| institution | Directory Open Access Journal |
| issn | 2672-0191 2055-0391 |
| language | English |
| last_indexed | 2024-12-17T00:19:15Z |
| publishDate | 2021-05-01 |
| publisher | Korean Society of Animal Sciences and Technology |
| record_format | Article |
| series | Journal of Animal Science and Technology |
| spelling | doaj.art-a5589233a1ba4e29b7e85ce7c8bc0b3b2022-12-21T22:10:37ZengKorean Society of Animal Sciences and TechnologyJournal of Animal Science and Technology2672-01912055-03912021-05-0163350150910.5187/jast.2021.e54jast-63-3-501Effects of dietary lysozyme supplementation on growth performance, nutrient digestibility, intestinal microbiota, and blood profiles of weanling pigs challenged with Escherichia coliJae Hong Park0Shanmugam Sureshkumar1In Ho Kim2Department of Animal Resource and Science, Dankook University, Department of Animal Resource and Science, Dankook University, Department of Animal Resource and Science, Dankook University, The aim of this was evaluate the efficacy of lysozyme on growth performance, nutrient digestibility, excreta microflora population, and blood profiles of weanling pigs under Escherichia coli (E. coli) challenge. A total of 30 piglets weaned at 25 days, 7.46 kg body weight, were assigned to three dietary treatments, composed of five replications, two piglets per replication, for 7 days. The dietary treatment groups were negative control (NC; without antibiotics and lysozyme), positive control (PC; NC + antibiotics), lysozyme (NC + 0.1% lysozyme). All piglets were challenged orally with 6 ml suspension, containing E. coli K88 (2 × 109 CFU/mL). Dietary supplementation with lysozyme and PC resulted in no significant differences in average daily gain and gain to feed efficiency. Weanling pigs fed with E. coli challenge with lysozyme and PC treatments had significantly enhanced nutrient retentions of dry matter and energy (p < 0.05); however, there was a tendency to increase nitrogen digestibility. Furthermore, dietary inclusion of lysozyme and antibiotics treatment groups had a beneficial effect on excreta, ileal, and cecal of the fecal microbial population as decreased E. coli (p < 0.05) counts, without effects on lactobacillus counts. A significant effect were observed on a white blood cells, epinephrine and cortisol concentrations were reduced in piglets fed diets containing E. coli challenge with lysozyme and antibiotics supplementation comparison with the NC group. Therefore, the present data indicate that lysozyme in diet could ameliorate the experimental stress response induced by E. coli in piglets by decreasing intestinal E. coli, white blood cells and stress hormones and improving nutrient digestibility.http://www.ejast.org/archive/view_article?pid=jast-63-3-501lysozymeescherichia coli challengeintestinal microfloraweaning pig |
| spellingShingle | Jae Hong Park Shanmugam Sureshkumar In Ho Kim Effects of dietary lysozyme supplementation on growth performance, nutrient digestibility, intestinal microbiota, and blood profiles of weanling pigs challenged with Escherichia coli Journal of Animal Science and Technology lysozyme escherichia coli challenge intestinal microflora weaning pig |
| title | Effects of dietary lysozyme supplementation on growth performance,
nutrient digestibility, intestinal microbiota, and blood profiles of weanling
pigs challenged with Escherichia coli |
| title_full | Effects of dietary lysozyme supplementation on growth performance,
nutrient digestibility, intestinal microbiota, and blood profiles of weanling
pigs challenged with Escherichia coli |
| title_fullStr | Effects of dietary lysozyme supplementation on growth performance,
nutrient digestibility, intestinal microbiota, and blood profiles of weanling
pigs challenged with Escherichia coli |
| title_full_unstemmed | Effects of dietary lysozyme supplementation on growth performance,
nutrient digestibility, intestinal microbiota, and blood profiles of weanling
pigs challenged with Escherichia coli |
| title_short | Effects of dietary lysozyme supplementation on growth performance,
nutrient digestibility, intestinal microbiota, and blood profiles of weanling
pigs challenged with Escherichia coli |
| title_sort | effects of dietary lysozyme supplementation on growth performance nutrient digestibility intestinal microbiota and blood profiles of weanling pigs challenged with escherichia coli |
| topic | lysozyme escherichia coli challenge intestinal microflora weaning pig |
| url | http://www.ejast.org/archive/view_article?pid=jast-63-3-501 |
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