Perioperative Coagulopathy in Patients with Normal Preoperative Coagulation Screen: A Couple of Coagulopathic Clinical Case Conundrums

Perioperative coagulopathy impacts patient outcome by influencing intraoperative hemodynamics and blood loss. We present two cases which despite having normal preoperative coagulation profiles and normotension during the surgery had intraoperative coagulopathy and unusual bleeding. These cases requi...

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Main Authors: Joseph N. Monteiro, Shwetal Goraksha, Ninad S. Dhokte, Balkrishna Padate
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd. 2020-06-01
Series:Journal of Neuroanaesthesiology and Critical Care
Subjects:
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0040-1712855
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author Joseph N. Monteiro
Shwetal Goraksha
Ninad S. Dhokte
Balkrishna Padate
author_facet Joseph N. Monteiro
Shwetal Goraksha
Ninad S. Dhokte
Balkrishna Padate
author_sort Joseph N. Monteiro
collection DOAJ
description Perioperative coagulopathy impacts patient outcome by influencing intraoperative hemodynamics and blood loss. We present two cases which despite having normal preoperative coagulation profiles and normotension during the surgery had intraoperative coagulopathy and unusual bleeding. These cases required a multidisciplinary approach to manage them successfully. A thorough knowledge of the coagulation cascade along with a high-degree of suspicion and early recognition of coagulation is required. Abnormalities are critical for a timely intervention. Point-of-care tests like thromboelastography (TEG) as well as platelet function studies helped us arrive at an early diagnosis and initiate prompt treatment.
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spelling doaj.art-a55e6863bebe4ec9a66827d82cf84a592022-12-21T22:10:54ZengThieme Medical and Scientific Publishers Pvt. Ltd.Journal of Neuroanaesthesiology and Critical Care2348-05482348-926X2020-06-01080214414610.1055/s-0040-1712855Perioperative Coagulopathy in Patients with Normal Preoperative Coagulation Screen: A Couple of Coagulopathic Clinical Case ConundrumsJoseph N. Monteiro0Shwetal Goraksha1Ninad S. Dhokte2Balkrishna Padate3Department of Anaesthesiology, P. D. Hinduja Hospital and Medical Research Centre. Mumbai, Maharashtra, IndiaDepartment of Anaesthesiology, P. D. Hinduja Hospital and Medical Research Centre. Mumbai, Maharashtra, IndiaDepartment of Anaesthesiology, P. D. Hinduja Hospital and Medical Research Centre. Mumbai, Maharashtra, IndiaDepartment of Hematology, P. D. Hinduja Hospital and Medical Research Centre. Mumbai, Maharashtra, IndiaPerioperative coagulopathy impacts patient outcome by influencing intraoperative hemodynamics and blood loss. We present two cases which despite having normal preoperative coagulation profiles and normotension during the surgery had intraoperative coagulopathy and unusual bleeding. These cases required a multidisciplinary approach to manage them successfully. A thorough knowledge of the coagulation cascade along with a high-degree of suspicion and early recognition of coagulation is required. Abnormalities are critical for a timely intervention. Point-of-care tests like thromboelastography (TEG) as well as platelet function studies helped us arrive at an early diagnosis and initiate prompt treatment.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0040-1712855thromboelastographythrombin activatable fibrinolysis inhibitorselective serotonin reuptake inhibitor
spellingShingle Joseph N. Monteiro
Shwetal Goraksha
Ninad S. Dhokte
Balkrishna Padate
Perioperative Coagulopathy in Patients with Normal Preoperative Coagulation Screen: A Couple of Coagulopathic Clinical Case Conundrums
Journal of Neuroanaesthesiology and Critical Care
thromboelastography
thrombin activatable fibrinolysis inhibitor
selective serotonin reuptake inhibitor
title Perioperative Coagulopathy in Patients with Normal Preoperative Coagulation Screen: A Couple of Coagulopathic Clinical Case Conundrums
title_full Perioperative Coagulopathy in Patients with Normal Preoperative Coagulation Screen: A Couple of Coagulopathic Clinical Case Conundrums
title_fullStr Perioperative Coagulopathy in Patients with Normal Preoperative Coagulation Screen: A Couple of Coagulopathic Clinical Case Conundrums
title_full_unstemmed Perioperative Coagulopathy in Patients with Normal Preoperative Coagulation Screen: A Couple of Coagulopathic Clinical Case Conundrums
title_short Perioperative Coagulopathy in Patients with Normal Preoperative Coagulation Screen: A Couple of Coagulopathic Clinical Case Conundrums
title_sort perioperative coagulopathy in patients with normal preoperative coagulation screen a couple of coagulopathic clinical case conundrums
topic thromboelastography
thrombin activatable fibrinolysis inhibitor
selective serotonin reuptake inhibitor
url http://www.thieme-connect.de/DOI/DOI?10.1055/s-0040-1712855
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AT ninadsdhokte perioperativecoagulopathyinpatientswithnormalpreoperativecoagulationscreenacoupleofcoagulopathicclinicalcaseconundrums
AT balkrishnapadate perioperativecoagulopathyinpatientswithnormalpreoperativecoagulationscreenacoupleofcoagulopathicclinicalcaseconundrums