Study of Caspase 8 Inhibition for the Management of Alzheimer’s Disease: A Molecular Docking and Dynamics Simulation

Study of Caspase 8 Inhibition for the Management of Alzheimer’s Disease: A Molecular Docking and Dynamics Simulation

Alzheimer’s disease (AD) is the most common type of dementia and usually manifests as diminished episodic memory and cognitive functions. Caspases are crucial mediators of neuronal death in a number of neurodegenerative diseases, and caspase 8 is considered a major therapeutic target in the context...

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Bibliographic Details
Main Authors: Syed Sayeed Ahmad, Meetali Sinha, Khurshid Ahmad, Mohammad Khalid, Inho Choi
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Molecules
Subjects:
Alzheimer’s disease
caspase 8
molecular dynamics
RMSD
RMSF
Online Access:https://www.mdpi.com/1420-3049/25/9/2071

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