TLR7 activation in M-CSF-dependent monocyte-derived human macrophages potentiates inflammatory responses and prompts neutrophil recruitment

TLR7 activation in M-CSF-dependent monocyte-derived human macrophages potentiates inflammatory responses and prompts neutrophil recruitment

Toll-like receptor 7 (TLR7) is an endosomal Pathogen-Associated Molecular Pattern (PAMP) receptor that senses single-stranded RNA (ssRNA) and whose engagement results in the production of type I IFN and pro-inflammatory cytokines upon viral exposure. Recent genetic studies have established that a dy...

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Bibliographic Details
Main Authors: Miriam Simón-Fuentes, Cristina Herrero, Lucia Acero-Riaguas, Concha Nieto, Fatima Lasala, Nuria Labiod, Joanna Luczkowiak, Bárbara Alonso, Rafael Delgado, Maria Colmenares, Ángel L. Corbí, Ángeles Domínguez-Soto
Format: Article
Language:English
Published: Karger Publishers 2023-04-01
Series:Journal of Innate Immunity
Online Access:https://www.karger.com/Article/FullText/530249

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https://www.karger.com/Article/FullText/530249

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