Buffer Components Incorporate into the Framework of Polyserotonin Nanoparticles and Films during Synthesis
Polyserotonin nanoparticles (PSeNP) and films are bioinspired nanomaterials that have potential in biomedical applications and surface coatings. As studies on polyserotonin (PSe) nanoparticles and films are still in their infancy, synthetic pathways and material development for this new class of nan...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-06-01
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| Series: | Nanomaterials |
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| Online Access: | https://www.mdpi.com/2079-4991/12/12/2027 |
| _version_ | 1827657980341911552 |
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| author | Keuna Jeon Justin Andrei Asuncion Alexander Lucien Corbett Tiange Yuan Meera Patel Nesha May Octavio Andoy Christian Titus Kreis Oleksandr Voznyy Ruby May Arana Sullan |
| author_facet | Keuna Jeon Justin Andrei Asuncion Alexander Lucien Corbett Tiange Yuan Meera Patel Nesha May Octavio Andoy Christian Titus Kreis Oleksandr Voznyy Ruby May Arana Sullan |
| author_sort | Keuna Jeon |
| collection | DOAJ |
| description | Polyserotonin nanoparticles (PSeNP) and films are bioinspired nanomaterials that have potential in biomedical applications and surface coatings. As studies on polyserotonin (PSe) nanoparticles and films are still in their infancy, synthetic pathways and material development for this new class of nanomaterial await investigation. Here, we sought to determine how different buffers used during the polymerization of serotonin to form nanoparticles and films impact the physicochemical properties of PSe materials. We show that buffer components are incorporated into the polymer matrix, which is also supported by density functional theory calculations. While we observed no significant differences between the elasticity of nanoparticles synthesized in the different buffers, the nanoscale surface properties of PSe films revealed dissimilarities in surface functional groups influenced by solvent molecules. Overall, the results obtained in this work can be used towards the rational design of PSe nanomaterials with tailored properties and for specific applications. |
| first_indexed | 2024-03-09T22:53:27Z |
| format | Article |
| id | doaj.art-a564a9d5e1954e5e85199f199d6d5177 |
| institution | Directory Open Access Journal |
| issn | 2079-4991 |
| language | English |
| last_indexed | 2024-03-09T22:53:27Z |
| publishDate | 2022-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nanomaterials |
| spelling | doaj.art-a564a9d5e1954e5e85199f199d6d51772023-11-23T18:16:18ZengMDPI AGNanomaterials2079-49912022-06-011212202710.3390/nano12122027Buffer Components Incorporate into the Framework of Polyserotonin Nanoparticles and Films during SynthesisKeuna Jeon0Justin Andrei Asuncion1Alexander Lucien Corbett2Tiange Yuan3Meera Patel4Nesha May Octavio Andoy5Christian Titus Kreis6Oleksandr Voznyy7Ruby May Arana Sullan8Department of Physical and Environmental Sciences, University of Toronto Scarborough, 1065 Military Trail, Toronto, ON M1C 1A4, CanadaDepartment of Physical and Environmental Sciences, University of Toronto Scarborough, 1065 Military Trail, Toronto, ON M1C 1A4, CanadaDepartment of Physical and Environmental Sciences, University of Toronto Scarborough, 1065 Military Trail, Toronto, ON M1C 1A4, CanadaDepartment of Physical and Environmental Sciences, University of Toronto Scarborough, 1065 Military Trail, Toronto, ON M1C 1A4, CanadaDepartment of Physical and Environmental Sciences, University of Toronto Scarborough, 1065 Military Trail, Toronto, ON M1C 1A4, CanadaDepartment of Physical and Environmental Sciences, University of Toronto Scarborough, 1065 Military Trail, Toronto, ON M1C 1A4, CanadaDepartment of Physical and Environmental Sciences, University of Toronto Scarborough, 1065 Military Trail, Toronto, ON M1C 1A4, CanadaDepartment of Physical and Environmental Sciences, University of Toronto Scarborough, 1065 Military Trail, Toronto, ON M1C 1A4, CanadaDepartment of Physical and Environmental Sciences, University of Toronto Scarborough, 1065 Military Trail, Toronto, ON M1C 1A4, CanadaPolyserotonin nanoparticles (PSeNP) and films are bioinspired nanomaterials that have potential in biomedical applications and surface coatings. As studies on polyserotonin (PSe) nanoparticles and films are still in their infancy, synthetic pathways and material development for this new class of nanomaterial await investigation. Here, we sought to determine how different buffers used during the polymerization of serotonin to form nanoparticles and films impact the physicochemical properties of PSe materials. We show that buffer components are incorporated into the polymer matrix, which is also supported by density functional theory calculations. While we observed no significant differences between the elasticity of nanoparticles synthesized in the different buffers, the nanoscale surface properties of PSe films revealed dissimilarities in surface functional groups influenced by solvent molecules. Overall, the results obtained in this work can be used towards the rational design of PSe nanomaterials with tailored properties and for specific applications.https://www.mdpi.com/2079-4991/12/12/2027polyserotonin nanoparticlespolyserotonin filmsnanomechanical properties of polyserotoninelasticity of polyserotoninbioinspired nanomaterialsatomic force microscopy (AFM) |
| spellingShingle | Keuna Jeon Justin Andrei Asuncion Alexander Lucien Corbett Tiange Yuan Meera Patel Nesha May Octavio Andoy Christian Titus Kreis Oleksandr Voznyy Ruby May Arana Sullan Buffer Components Incorporate into the Framework of Polyserotonin Nanoparticles and Films during Synthesis Nanomaterials polyserotonin nanoparticles polyserotonin films nanomechanical properties of polyserotonin elasticity of polyserotonin bioinspired nanomaterials atomic force microscopy (AFM) |
| title | Buffer Components Incorporate into the Framework of Polyserotonin Nanoparticles and Films during Synthesis |
| title_full | Buffer Components Incorporate into the Framework of Polyserotonin Nanoparticles and Films during Synthesis |
| title_fullStr | Buffer Components Incorporate into the Framework of Polyserotonin Nanoparticles and Films during Synthesis |
| title_full_unstemmed | Buffer Components Incorporate into the Framework of Polyserotonin Nanoparticles and Films during Synthesis |
| title_short | Buffer Components Incorporate into the Framework of Polyserotonin Nanoparticles and Films during Synthesis |
| title_sort | buffer components incorporate into the framework of polyserotonin nanoparticles and films during synthesis |
| topic | polyserotonin nanoparticles polyserotonin films nanomechanical properties of polyserotonin elasticity of polyserotonin bioinspired nanomaterials atomic force microscopy (AFM) |
| url | https://www.mdpi.com/2079-4991/12/12/2027 |
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