Correlation between internal pudendal artery stenosis and erectile dysfunction in patients with suspected coronary artery disease.
<h4>Background</h4>Stenoses of internal pudendal arteries (IPAs) appear to be related to erectile dysfunction (ED). Nevertheless, the correlation between the severity of ED and stenosis of the IPAs is not well established.<h4>Objectives</h4>To evaluate angiographic findings o...
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2019-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0225179 |
| _version_ | 1818443950704295936 |
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| author | Ha-Wook Park Sung-Ho Her Bong-Hee Park Dong-Seok Han Seung Mo Yuk Dae-Won Kim Chang Shik Youn Hoon Jang |
| author_facet | Ha-Wook Park Sung-Ho Her Bong-Hee Park Dong-Seok Han Seung Mo Yuk Dae-Won Kim Chang Shik Youn Hoon Jang |
| author_sort | Ha-Wook Park |
| collection | DOAJ |
| description | <h4>Background</h4>Stenoses of internal pudendal arteries (IPAs) appear to be related to erectile dysfunction (ED). Nevertheless, the correlation between the severity of ED and stenosis of the IPAs is not well established.<h4>Objectives</h4>To evaluate angiographic findings of IPAs in patients with suspected coronary artery disease (CAD) and to assess the correlation between the severity of ED and IPA stenosis.<h4>Materials and methods</h4>Ninety-one patients who were scheduled for cardiac angiogram (CAG) because of suspected CAD participated. ED was assessed using the International Index of Erectile Function (IIEF) questionnaire. Erectile function (EF) domain scoring was used to assess the severity of ED: severe (EF score = 1-10); moderate (11-16); mild-moderate (17-21); mild (22-25); and no ED (26-30). Angiography was performed in bilateral common, internal iliac, and IPAs and the location and extent of stenoses were measured. We divided patients according to those with maximum stenosis of less than 50% (Group I) and those with more than 50% (Group II), regardless of direction.<h4>Results</h4>We diagnosed 88 patients (88/91, 96.70%) with ED. There was no correlation between increasing age and severity of ED (r = - 0.063, p = 0.555). There were 72 patients in Group I and 19 in Group II. In Group I, 62 patients were diagnosed with ED even though there was no stenosis. There was no significant correlation between the severity of ED and the extent of stenosis in IPAs (r = -0.118, p = 0.265).<h4>Conclusions</h4>There was no significant correlation between the severity of ED and the extent of stenosis of IPAs. We believe that this is because the progression of ED is induced by endothelial cell dysfunction, not by mechanical obstruction leading to blood flow reduction. |
| first_indexed | 2024-12-14T19:08:11Z |
| format | Article |
| id | doaj.art-a56583b1751742f3b8c500d6b8540cbb |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-14T19:08:11Z |
| publishDate | 2019-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-a56583b1751742f3b8c500d6b8540cbb2022-12-21T22:50:48ZengPublic Library of Science (PLoS)PLoS ONE1932-62032019-01-011411e022517910.1371/journal.pone.0225179Correlation between internal pudendal artery stenosis and erectile dysfunction in patients with suspected coronary artery disease.Ha-Wook ParkSung-Ho HerBong-Hee ParkDong-Seok HanSeung Mo YukDae-Won KimChang Shik YounHoon Jang<h4>Background</h4>Stenoses of internal pudendal arteries (IPAs) appear to be related to erectile dysfunction (ED). Nevertheless, the correlation between the severity of ED and stenosis of the IPAs is not well established.<h4>Objectives</h4>To evaluate angiographic findings of IPAs in patients with suspected coronary artery disease (CAD) and to assess the correlation between the severity of ED and IPA stenosis.<h4>Materials and methods</h4>Ninety-one patients who were scheduled for cardiac angiogram (CAG) because of suspected CAD participated. ED was assessed using the International Index of Erectile Function (IIEF) questionnaire. Erectile function (EF) domain scoring was used to assess the severity of ED: severe (EF score = 1-10); moderate (11-16); mild-moderate (17-21); mild (22-25); and no ED (26-30). Angiography was performed in bilateral common, internal iliac, and IPAs and the location and extent of stenoses were measured. We divided patients according to those with maximum stenosis of less than 50% (Group I) and those with more than 50% (Group II), regardless of direction.<h4>Results</h4>We diagnosed 88 patients (88/91, 96.70%) with ED. There was no correlation between increasing age and severity of ED (r = - 0.063, p = 0.555). There were 72 patients in Group I and 19 in Group II. In Group I, 62 patients were diagnosed with ED even though there was no stenosis. There was no significant correlation between the severity of ED and the extent of stenosis in IPAs (r = -0.118, p = 0.265).<h4>Conclusions</h4>There was no significant correlation between the severity of ED and the extent of stenosis of IPAs. We believe that this is because the progression of ED is induced by endothelial cell dysfunction, not by mechanical obstruction leading to blood flow reduction.https://doi.org/10.1371/journal.pone.0225179 |
| spellingShingle | Ha-Wook Park Sung-Ho Her Bong-Hee Park Dong-Seok Han Seung Mo Yuk Dae-Won Kim Chang Shik Youn Hoon Jang Correlation between internal pudendal artery stenosis and erectile dysfunction in patients with suspected coronary artery disease. PLoS ONE |
| title | Correlation between internal pudendal artery stenosis and erectile dysfunction in patients with suspected coronary artery disease. |
| title_full | Correlation between internal pudendal artery stenosis and erectile dysfunction in patients with suspected coronary artery disease. |
| title_fullStr | Correlation between internal pudendal artery stenosis and erectile dysfunction in patients with suspected coronary artery disease. |
| title_full_unstemmed | Correlation between internal pudendal artery stenosis and erectile dysfunction in patients with suspected coronary artery disease. |
| title_short | Correlation between internal pudendal artery stenosis and erectile dysfunction in patients with suspected coronary artery disease. |
| title_sort | correlation between internal pudendal artery stenosis and erectile dysfunction in patients with suspected coronary artery disease |
| url | https://doi.org/10.1371/journal.pone.0225179 |
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