The Ultraviolet Irradiation of Keratinocytes Induces Ectopic Expression of LINE-1 Retrotransposon Machinery and Leads to Cellular Senescence
Retrotransposons have played an important role in evolution through their transposable activity. The largest and the only currently active human group of mobile DNAs are the <i>LINE-1</i> retrotransposons. The ectopic expression of <i>LINE-1</i> has been correlated with genom...
Main Authors: | Fadi Touma, Marine Lambert, Amelia Martínez Villarreal, Jennifer Gantchev, Brandon Ramchatesingh, Ivan V. Litvinov |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-11-01
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Series: | Biomedicines |
Subjects: | |
Online Access: | https://www.mdpi.com/2227-9059/11/11/3017 |
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