The Ultraviolet Irradiation of Keratinocytes Induces Ectopic Expression of LINE-1 Retrotransposon Machinery and Leads to Cellular Senescence

The Ultraviolet Irradiation of Keratinocytes Induces Ectopic Expression of LINE-1 Retrotransposon Machinery and Leads to Cellular Senescence

Retrotransposons have played an important role in evolution through their transposable activity. The largest and the only currently active human group of mobile DNAs are the <i>LINE-1</i> retrotransposons. The ectopic expression of <i>LINE-1</i> has been correlated with genom...

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Bibliographic Details
Main Authors: Fadi Touma, Marine Lambert, Amelia Martínez Villarreal, Jennifer Gantchev, Brandon Ramchatesingh, Ivan V. Litvinov
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Biomedicines
Subjects:
long interspersed nucleotide element-1 (LINE-1)
phototherapy
keratinocytes
BB-UVB
NB-UVB
genomic instability
Online Access:https://www.mdpi.com/2227-9059/11/11/3017

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