Increased angiogenesis and improved left ventricular function after transplantation of myoblasts lacking the MyoD gene into infarcted myocardium.

Increased angiogenesis and improved left ventricular function after transplantation of myoblasts lacking the MyoD gene into infarcted myocardium.

Skeletal myoblast transplantation has therapeutic potential for repairing damaged heart. However, the optimal conditions for this transplantation are still unclear. Recently, we demonstrated that satellite cell-derived myoblasts lacking the MyoD gene (MyoD(-/-)), a master transcription factor for sk...

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Bibliographic Details
Main Authors: Yasuhiro Nakamura, Yoko Asakura, Bryan A Piras, Hiroyuki Hirai, Christopher T Tastad, Mayank Verma, Amanda J Christ, Jianyi Zhang, Takanori Yamazaki, Minoru Yoshiyama, Atsushi Asakura
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3404994?pdf=render

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