Pan-cancer analysis reveals distinct clinical, genomic, and immunological features of the LILRB immune checkpoint family in acute myeloid leukemia

Pan-cancer analysis reveals distinct clinical, genomic, and immunological features of the LILRB immune checkpoint family in acute myeloid leukemia

Leukocyte immunoglobulin (Ig)-like receptor Bs (LILRBs), a family of type I transmembrane glycoproteins, are known to inhibit immune activation. Here, we comprehensively evaluated the molecular, prognostic, and immunological characteristics of LILRB members in a broad spectrum of cancer types, focus...

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Podrobná bibliografie
Hlavní autoři: Zi-jun Xu, Xin-long Zhang, Ye Jin, Shi-sen Wang, Yu Gu, Ji-chun Ma, Xiang-mei Wen, Jia-yan Leng, Zhen-wei Mao, Jiang Lin, Jun Qian
Médium: Článek
Jazyk:English
Vydáno: Elsevier 2022-09-01
Edice:Molecular Therapy: Oncolytics
Témata:
LILRBs
immune checkpoint genes
immune evasion
pan-cancer
leukemia
immunotherapy
On-line přístup:http://www.sciencedirect.com/science/article/pii/S2372770522000778

Internet

http://www.sciencedirect.com/science/article/pii/S2372770522000778

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