Artificially introduced aneuploid chromosomes assume a conserved position in colon cancer cells.

BACKGROUND:Chromosomal aneuploidy is a defining feature of carcinomas. For instance, in colon cancer, an additional copy of Chromosome 7 is not only observed in early pre-malignant polyps, but is faithfully maintained throughout progression to metastasis. These copy number changes show a positive co...

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Detaylı Bibliyografya
Asıl Yazarlar: Kundan Sengupta, Madhvi B Upender, Linda Barenboim-Stapleton, Quang Tri Nguyen, Stephen M Wincovitch, Susan H Garfield, Michael J Difilippantonio, Thomas Ried
Materyal Türü: Makale
Dil:English
Baskı/Yayın Bilgisi: Public Library of Science (PLoS) 2007-02-01
Seri Bilgileri:PLoS ONE
Online Erişim:http://europepmc.org/articles/PMC1805818?pdf=render