Ratio and difference of the cross-sectional area of median nerve to ulnar nerve in diagnosing carpal tunnel syndrome: a case control study
Abstract Background To evaluate the diagnostic accuracy of the median-to-ulnar nerve ratio (MUR) and the median-to-ulnar nerve difference (MUD) in patients with carpal tunnel syndrome (CTS). Methods In this study, 32 patients with CTS and 32 healthy volunteers were evaluated. All participants receiv...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2019-07-01
|
| Series: | BMC Medical Imaging |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12880-019-0351-3 |
| _version_ | 1818885649887920128 |
|---|---|
| author | Yi-Wei Chang Tsung-Cheng Hsieh I-Shiang Tzeng Valeria Chiu Pei-Jung Huang Yi-Shiung Horng |
| author_facet | Yi-Wei Chang Tsung-Cheng Hsieh I-Shiang Tzeng Valeria Chiu Pei-Jung Huang Yi-Shiung Horng |
| author_sort | Yi-Wei Chang |
| collection | DOAJ |
| description | Abstract Background To evaluate the diagnostic accuracy of the median-to-ulnar nerve ratio (MUR) and the median-to-ulnar nerve difference (MUD) in patients with carpal tunnel syndrome (CTS). Methods In this study, 32 patients with CTS and 32 healthy volunteers were evaluated. All participants received a series of tests and ultrasound examination for the evaluation of the following criteria: cross-sectional area of the median nerve at the pisiform level (CSA-P), swelling ratio (SR), MUR, MUD, and flattening ratio (FR). Results CSA-P, SR, MUR, and MUD were all significantly larger in the patients with CTS than in the healthy volunteers. The areas under the receiver operator characteristic curves of MUD, MUR, CSA-P, and SR were 0.78, 0.75, 0.70, and 0.61 respectively. MUD had higher sensitivity (84%) than MUR, CSA-P, and SR (sensitivity: 63, 63, and 53%, respectively). Conclusions By using the ulnar nerve area at the pisiform level as an internal control parameter, the MUD and MUR methods showed higher diagnostic accuracy than SR in patients with CTS. Further application of these methods in research and clinical settings is recommended. Trial registration Clinicaltrial.gov NCT03033173. Registered 18 January 2017. Retrospectively registered. |
| first_indexed | 2024-12-19T16:08:48Z |
| format | Article |
| id | doaj.art-a56e7db7062b442898ab0f987ebbb26f |
| institution | Directory Open Access Journal |
| issn | 1471-2342 |
| language | English |
| last_indexed | 2024-12-19T16:08:48Z |
| publishDate | 2019-07-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Medical Imaging |
| spelling | doaj.art-a56e7db7062b442898ab0f987ebbb26f2022-12-21T20:14:47ZengBMCBMC Medical Imaging1471-23422019-07-011911910.1186/s12880-019-0351-3Ratio and difference of the cross-sectional area of median nerve to ulnar nerve in diagnosing carpal tunnel syndrome: a case control studyYi-Wei Chang0Tsung-Cheng Hsieh1I-Shiang Tzeng2Valeria Chiu3Pei-Jung Huang4Yi-Shiung Horng5Department of Physical Medicine and Rehabilitation Taipei Tzuchi Hospital, Buddhist Tzuchi Medical FoundationInstitute of Medical Sciences, Tzu Chi UniversityDepartment of Research Taipei Tzuchi Hospital, Buddhist Tzuchi Medical FoundationDepartment of Physical Medicine and Rehabilitation Taipei Tzuchi Hospital, Buddhist Tzuchi Medical FoundationDepartment of Physical Medicine and Rehabilitation Taipei Tzuchi Hospital, Buddhist Tzuchi Medical FoundationDepartment of Physical Medicine and Rehabilitation Taipei Tzuchi Hospital, Buddhist Tzuchi Medical FoundationAbstract Background To evaluate the diagnostic accuracy of the median-to-ulnar nerve ratio (MUR) and the median-to-ulnar nerve difference (MUD) in patients with carpal tunnel syndrome (CTS). Methods In this study, 32 patients with CTS and 32 healthy volunteers were evaluated. All participants received a series of tests and ultrasound examination for the evaluation of the following criteria: cross-sectional area of the median nerve at the pisiform level (CSA-P), swelling ratio (SR), MUR, MUD, and flattening ratio (FR). Results CSA-P, SR, MUR, and MUD were all significantly larger in the patients with CTS than in the healthy volunteers. The areas under the receiver operator characteristic curves of MUD, MUR, CSA-P, and SR were 0.78, 0.75, 0.70, and 0.61 respectively. MUD had higher sensitivity (84%) than MUR, CSA-P, and SR (sensitivity: 63, 63, and 53%, respectively). Conclusions By using the ulnar nerve area at the pisiform level as an internal control parameter, the MUD and MUR methods showed higher diagnostic accuracy than SR in patients with CTS. Further application of these methods in research and clinical settings is recommended. Trial registration Clinicaltrial.gov NCT03033173. Registered 18 January 2017. Retrospectively registered.http://link.springer.com/article/10.1186/s12880-019-0351-3Carpal tunnel syndromeMedian nerveUlnar nerveUltrasoundMedian nerve entrapment |
| spellingShingle | Yi-Wei Chang Tsung-Cheng Hsieh I-Shiang Tzeng Valeria Chiu Pei-Jung Huang Yi-Shiung Horng Ratio and difference of the cross-sectional area of median nerve to ulnar nerve in diagnosing carpal tunnel syndrome: a case control study BMC Medical Imaging Carpal tunnel syndrome Median nerve Ulnar nerve Ultrasound Median nerve entrapment |
| title | Ratio and difference of the cross-sectional area of median nerve to ulnar nerve in diagnosing carpal tunnel syndrome: a case control study |
| title_full | Ratio and difference of the cross-sectional area of median nerve to ulnar nerve in diagnosing carpal tunnel syndrome: a case control study |
| title_fullStr | Ratio and difference of the cross-sectional area of median nerve to ulnar nerve in diagnosing carpal tunnel syndrome: a case control study |
| title_full_unstemmed | Ratio and difference of the cross-sectional area of median nerve to ulnar nerve in diagnosing carpal tunnel syndrome: a case control study |
| title_short | Ratio and difference of the cross-sectional area of median nerve to ulnar nerve in diagnosing carpal tunnel syndrome: a case control study |
| title_sort | ratio and difference of the cross sectional area of median nerve to ulnar nerve in diagnosing carpal tunnel syndrome a case control study |
| topic | Carpal tunnel syndrome Median nerve Ulnar nerve Ultrasound Median nerve entrapment |
| url | http://link.springer.com/article/10.1186/s12880-019-0351-3 |
| work_keys_str_mv | AT yiweichang ratioanddifferenceofthecrosssectionalareaofmediannervetoulnarnerveindiagnosingcarpaltunnelsyndromeacasecontrolstudy AT tsungchenghsieh ratioanddifferenceofthecrosssectionalareaofmediannervetoulnarnerveindiagnosingcarpaltunnelsyndromeacasecontrolstudy AT ishiangtzeng ratioanddifferenceofthecrosssectionalareaofmediannervetoulnarnerveindiagnosingcarpaltunnelsyndromeacasecontrolstudy AT valeriachiu ratioanddifferenceofthecrosssectionalareaofmediannervetoulnarnerveindiagnosingcarpaltunnelsyndromeacasecontrolstudy AT peijunghuang ratioanddifferenceofthecrosssectionalareaofmediannervetoulnarnerveindiagnosingcarpaltunnelsyndromeacasecontrolstudy AT yishiunghorng ratioanddifferenceofthecrosssectionalareaofmediannervetoulnarnerveindiagnosingcarpaltunnelsyndromeacasecontrolstudy |