High EZH2 Protein Expression Is a Poor Prognostic Predictor in IDH1 R132H-Negative Gliomas

High EZH2 Protein Expression Is a Poor Prognostic Predictor in IDH1 R132H-Negative Gliomas

Accumulating data indicates that enhancer of zeste homology 2 (EZH2) and isocitrate dehydrogenase 1 (IDH1) are implicated in promoting tumourigenesis in a myriad of malignancies including gliomas. We aimed to determine the immunoexpression of EZH2 in gliomas and its correlation with clinicopathologi...

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Bibliographic Details
Main Authors: Yin Ping Wong, Roziasyazni Che Abdul Aziz, Azimatun Noor Aizuddin, Muhamad Fakhri Mohd Saleh, Roslina Mohd Arshad, Geok Chin Tan
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Diagnostics
Subjects:
EZH2
glioma
IDH1 R132H
immunohistochemistry
overall survival
prognosis
Online Access:https://www.mdpi.com/2075-4418/12/10/2383

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