A platform of assays for the discovery of anti-Zika small-molecules with activity in a 3D-bioprinted outer-blood-retina model.

A platform of assays for the discovery of anti-Zika small-molecules with activity in a 3D-bioprinted outer-blood-retina model.

The global health emergency posed by the outbreak of Zika virus (ZIKV), an arthropod-borne flavivirus causing severe neonatal neurological conditions, has subsided, but there continues to be transmission of ZIKV in endemic regions. As such, there is still a medical need for discovering and developin...

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Bibliographic Details
Main Authors: Dorjbal Dorjsuren, Richard T Eastman, Min Jae Song, Adam Yasgar, Yuchi Chen, Kapil Bharti, Alexey V Zakharov, Ajit Jadhav, Marc Ferrer, Pei-Yong Shi, Anton Simeonov
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0261821

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